Mukati
Kunyanyisa kudya hakuzi kunzi chirwere chenyika yakaguta zvakakwana pasina. Hupenyu hwemazuva ano hunongobatsira mukusimudzira kwekupindwa muropa uku. Kunonoka kudya kwemanheru muvhiki rese rekushanda. Mabiko emabiko ane zvakawanda zvekudya zvinokuvadza. Mhuri bhaisikopo kuongororwa kwesandwiches uye zvinwiwa. Mutengo wepfupi-wenguva yekunakidzwa kwemabhureki eruwa kazhinji haufadzi zviratidzo zvekudya zvakanyanya: huremu mushure mekudya, kusagadzikana mudumbu, kuzvimba, kufufutirwa. Uye, kana muviri ukasatsungirira, mishonga yekuvandudza kugaya inouya kununura. Vanoshanda sei? Dzese dzinoshanda here? Ndiani anofanira kutora uye riini?
Chokwadi # 1. Enzymes inodiwa pakujairika kugaya
Zvinozivikanwa kuti kunzwa kwekuguta kunouya zvishoma nezvishoma. Sezvo dumbu rizere nechikafu, iyo satiety hormone leptin inotanga kugadzirwa. Inokanganisa magumo etsinga mudumbu, uye chiratidzo chinotumirwa kuuropi kuti muviri uzere. Paavhareji, maitiro acho anotora maminetsi makumi matatu1. Izvi zvakakwana kuti uve nenguva yekuzadza dumbu rako nechimwe chikafu.
Kuwedzeredza kunoita kuti iinzwe nekunzwa kwakasiyana siyana. Isu tinoshungurudzwa nehuremu mudumbu, kuzvimba, kazhinji kusagadzikana. Izvi zvinokonzerwa nekuti hapana akakwana ekugaya enzyme anogadzirwa nerwatata, nekuti huwandu hwechikafu hwakanyanya.
Mune ino kesi, inoda zvimwe zviwanikwa. Basa ravo rinotorwa nemishonga yekuvandudza kugaya, kana kugadzirira enzyme. Ivo vanopa iwo anodikanwa kugoverwa kwema enzymes ayo anogadzira chikafu uye anobatsira mukukwikwidza kwakaringana kwehutano.
Kupesana nemamiriro ezvakaipa, zvisina kugadzikana chikafu, zvinetso zvakakomba zvinogona kumuka. Semuenzaniso, kurwadziwa kwehana, kusvotwa, manyoka, kurwadziwa mudumbu. Nekudaro, iyo yese yekugaya system inotambura.
Chokwadi # 2. Enzymes inodiwa pakudya kwese, zvisinei nehuwandu
Iyo pancreas inogadzira ma enzymes pakudya kwese, kunyangwe nechikafu chidiki. Panguva imwecheteyo, ine enzyme yayo yakagadzirirwa mhando yega yega yezvinovaka muviri. Saka, lipase inoputsa mafuta, protease inobatsira kugaya mapuroteni, amylase inoshandura akaomesesa makabhohaidhiretsi kuita nyore.
Kana huremu uye kusagadzikana zvichiitika nguva nenguva mushure mekudya, izvi zvinogona kuratidza kuti hapana maenzymes akakwana anogadzirwa nerwatata. Panogona kuve nezvakawanda zvikonzero: kudya zvisina kukodzera, kushanduka mukudya, shanduko ine chekuita nezera, kutadza kwehomoni, zvirwere zvinowirirana.
Ndicho chikonzero nei pancreas inoda vabatsiri nenzira yekugadzirira enzyme. Izvo zvakakosha kuti uzive kuti ivo havadzikise kugadzirwa kwayozvachose 2, Kukubvumidza iwe kugadzirisa chikafu zvakanaka uye zvine mutsindo. Uye sezvo vachitsiva ma enzymes emuviri, vanofanirwa kuita nechikafu sekunge chakagadzirwa pachavo.
Chokwadi # 3. Enzymes inoshanda mumatumbu, kwete mudumbu
Isu tose tinoyeuka kuti kugayiwa kwekudya kunotanga kana tangotumira chidimbu chekutanga chekudya mumuromo medu. Mate ane ma enzymes anotanga kugaya, anopfavisa chikafu uye anobatsira kuti apfuure nechepaguso. Dumbu rinotangawo kuburitsa muto wegastric wekupatsanura chikafu.
Asi kupatsanurwa kukuru kwechikafu hakuitike mudumbu, asi zvishoma-gare gare-kanopinda mumatumbu. Panguva imwecheteyo, zvinovaka muviri zvakafanana zvinoumbwa zvekuti muviri unofanirwa kuwana nguva yekufungidzira muhuwandu hwakazara kwazvo. Kana paine chero huremu kana kusagadzikana mushure mekudya, kugadzirira enzyme kunogona kushandiswa pano. Asi havazi vese vanokwanisa kusvika kumatumbu panguva imwechete nechikafu kana kumisikidzwa zvishoma nezvishoma. Ipapo muviri unorasikirwa nechikamu chinobatika che "mafuta", uye nekudaro huremu uye kusagadzikana mushure mekudya zvinogona kugara kwenguva yakati.
Panyaya iyi, gadziriro ye enzyme Creon® 10000 inogona kuve mubatsiri akatendeka. Inopinda mumatumbu panguva imwe chete nechikafu uye inoitwa mushure memaminitsi gumi nemashanu, kubvisa huremu mushure mekudya, kusagadzikana mudumbu, kuzvimba, kuwedzera gasi kuumbwa uye kumwe kusanzwisisika.3 Asi zvinonyanya kukosha, izvo zvinovaka muviri zvinovhenekwa nemazvo uye zvakaenzana.
Chokwadi # 4. Minimicrospheres ndiyo yazvino fomati yema enzymes4
Mazhinji enzyme gadziriro ine imwechete uye yakafanana chinhu chinoshanda - pancreatin. Kuumbwa kwema enzymes ayo kunoenderana zvachose neaya anogadzirwa nerwatata. Hunyengeri huri mune chokwadi chekuti hausi mushonga wega wega unokwanisa kuendesa chinhu chinoshanda chaizvo sekufunga - kumatumbu.
Mhando dzakajairika dzekusunungurwa kwema enzymes mapiritsi uye magera. Asi vane chakakosha kudzora. Nekuda kwechimiro chose, mapiritsi haakwanise kusanganisa zvakaenzana nechikafu chiri mudumbu uye kupfuura mumatumbu nechikamu chimwe nechimwe chazvo. Ndosaka chikamu chavo chichienda mumatumbu pamwe nechikafu, izvo zvingangodaro zvisina kukwana kugaya zvizere kwezvose zvadyiwa. Panguva imwecheteyo, mamwe ma enzymes anogona kugara mudumbu, uye isu tatoona kuti gadziriro ye enzyme inova isingabatsiri mudumbu. Uye zvakare, mapiritsi anogona kunetsa kumedza, kunyanya kune vana vadiki nevakura. Kuedza kupwanya kana kukuya chichava chikanganiso, nekuti izvi zvinoparadza ganda rekudzivirira repiritsi, uye nharaunda ine acidic yemudumbu inoparadza maenzymes.
Chimwe chinhu chinhu "akachenjera" makomputa ekugaya Creon®. Imwe neimwe yakadaro capsule ine mazana ezvimedu-minimicrospheres, ine dhayamita ingangoita 1.15mm3. Aya madiki macospospres ane patent uye anongowanikwa chete mukugadzirira Creon®5. Iyo inoratidzwa kuti idiki iyo enzyme particles, iyo inoshanda zvakanyanya mushonga3 inogona kushanda.
Mune fomu iyi, inosanganisa zvirinani nechikafu mudumbu uye panguva imwechete inopfuura ichienda mumatumbu. Chii chinonyanya kukosha, pamusoro pekapisi, imwe neimwe yemamiriro ekunze inodzivirirwa neganda risingapfuure acid. Inovatendera kuti "vapone" munzvimbo ine acidic yemudumbu uye nekuendesa yakanyanya ma enzyme anoshanda zvakananga kumatumbu3. Kutenda kune ino mashandiro ekuita, kutora Creon® inobatsira kugaya kuti ive yechisikigo sezvazvinogona, izvo zvino chengetedza kugaya kwakakwana kwechikafu uye kuunganidzwa kwehutano hwese.3
Chokwadi # 5. Kushaikwa kwema enzymes kunokanganisa muviri wese
Kushaikwa kwemakemikari kunokanganisa muviri wese6. Kudya zvakawandisa kunokuvadzawo mamwe masisitimu emuviri. Kuzadza chikafu chisina kuyerwa, dumbu rinoteerera rinotambanudza madziro nekuwedzera saizi. Saka inogona kumanikidza nhengo dzechipfuva, spleen, ura uye kukanganisa basa ravo rakazara.
Mukufamba kwenguva, kugara uchidya zvakanyanya kunogona kukonzera kufutisa6. Mamwe mapaundi anopa imwe mutoro pamoyo6. Mushure mezvose, iye, sepombi ine simba, anofanirwa kupomba ropa munzira refu.
Kunyanyisa kudya uye kunyanya kufuta kunogona kutungamira kumatambudziko emagetsi7. Majoini nemuzongoza zvinosangana nemutoro wakakura. Kuchinja kune ngozi zvikuru kunoitika muchiropa. Kutaura zvazviri, chiropa chechiropa chinoshanduka zvishoma nezvishoma kuva mafuta7. Chirwere cheshuga mellitus uye kushaya hope zvinogona kazhinji kukura8.
Kubatsira muviri kugaya chikafu, inoda kugadzirira enzyme. Ivo vanobatsira kumisikidza maficha ekuzeya uye metabolism, izvo zvinopa kune rakanyatso rongedzwa basa reimwe nhengo uye masisitimu.
Kune zviratidzo zvekunyanyisa kudya, 1-2 makapisi eCreon® 10000 yakwana - iyi ndiyo yakakwana huwandu hwemakemikari ekuvandudza kugaya. Unogona kutora Creon® kune wese munhu uye chero zera, kunyangwe vakadzi vane nhumbu uye vana vadiki kubva pakuzvarwa9. Zviri nani kuita izvi panguva yekudya kana pakarepo mushure, uine shoma mvura9.
Nechimwe chikonzero kana chimwe chikonzero, muviri unowanzo kushaya makemikari ekugaya. Nzira yekumhanyisa yekugadzirisa kushomeka kwavo ndeyekubatsira kugadzirira enzyme. Panguva imwecheteyo, zvakakosha kuti vashande nekukasira, nemazvo uye nemazvo sezvinobvira. Iyi ndiyo kiyi kune yakazara-yakazara kugaya uye inogadzira kugadzirwa kwezvinhu zvinobatsira. Uye pamwe navo - hutano hwakanaka uye hutano hwemuviri wese sewakazara.
1. Poltyrev SS Physiology yekugaya: bhuku. Chinyorwa. - Moscow: Chikoro chepamusoro, 2003. - p. 386.
2. Belmer SV, Gasilina TV Kugaya kudya kusakwana kwepancreas muvana. Kusiyanisa nzira / / Gomarara repazamu, Amai neMwana. Pediatrics, 2007. - Nha.
3. Löhr JM, Hummel FM, Pirilis KT et al. Zvivakwa zveakasiyana pancreatin gadziriro inoshandiswa mupancreatic exocrine kusakwana // Eur J Gastroenterol Hepatol., 2009; 21 (9): 1024-31.
4. 24.
5. Iyo chete pancreatin mishonga iri muchimiro cheimicrospheres yakanyoreswa mudunhu reRussian Federation, maererano neHurumende Rejista yeZvemitemo Zvita sa05.04.2019 / Source http://www.freepatent.ru/images/patents/52 /2408257/patent-2408257.pdf RU 2 408 364 C2 kupinda kubva 17.04.2019 uye http://www.freepatent.ru/images/patents/18/2440101/patent-2440101.pdf RU 2 440 101 C2 kupinda kubva pa17.04.2019. .XNUMX.
6. Lyubimova ZV Kushushikana kwekudya. Inobudirira nzira dzokurapa. - Moscow: Eksmo, 2009. - p. 117.
7. Trofimov S. Ya. Iyo yekugaya system. Zvirwere zvemukati. - M.: Prosveshchenie, 2005. - p. 201.
8. Yakovlev MV Yakajairika anatomi yemunhu: manotsi ehurukuro. - Moscow: Chikoro chepamusoro, 2003. - p. 312.
9. Mirayiridzo yekushandisa kwekurapa kwechirwere Creon® 10000 kubva 11.05.2018.
Izvo zvinhu zvakagadzirwa nerutsigiro rweAbbott Kambani kuitira kuwedzera murwere kuziva nezve mamiriro ehutano.
RUCRE191033 kubva 17.04.2019