Ataxia, chii ichocho?

Ataxia haisi chirwere pachayo, asi a chiratidzo izvo zvinobva kukuvadza kune cerebellum (chikamu cheuropi chinodzora kubatana kwemhasuru).

Ataxia inosanganisira kurasikirwa kwekubatana mumhasuru dzemaoko nemakumbo panguva yekufamba kwekuzvidira sekufamba kana kubata zvinhu. Ataxia inogonawo kukanganisa passwords, ivo kufamba kwemaziso uyekukwanisa kumedza. Ataxia inonziwo cerebellar ataxia kana cerebellar syndrome.

Kune zvakare akawanda akasiyana eataxies nhaka. Aya ndiwo zvirwere zvetsinga uye genetic zvinokanganisa cerebellum. Ivo kazhinji yenguva inoderera, kureva kuti iyo matambudziko ekubatanidza wedzera kujeka nekufamba kwenguva.

Zvinokonzera

Ataxia inogona kukonzerwa nemamiriro akawanda:

• Un head trauma. Kukuvadza kunokonzerwa kumusana kana uropi semugumisiro wetsaona yemotokari, somuenzaniso.
• A cerebrovascular tsaona (stroke) kana kurwisa kwechikafu chinokanganisa (TIA kana mini-stroke), kureva kuvharirwa kwenguva pfupi kwe cerebral artery iyo inogadzirisa zvakasikwa, pasina kusiya chero mhedzisiro.
• A cerebral palsy. Kukuvadzwa kuhuropi pamberi, panguva kana nguva pfupi mushure mekuzvarwa kunokanganisa kurongeka kwekufamba.
• Matambudziko anotevera a hutachiona hutachiona senge chickenpox kana Epstein-Barr virus.
• Multiple sclerosis.
• Kuita kune chepfu kune zvinorema simbi, senge lead kana mercury kana zvinonyungudutsa.
• A maitiro kune mimwe mishonga, zvakaita se barbituriques (semuenzaniso phenobarbital) kana kunyaradza (semuenzaniso benzodiazepines), inoshandiswa kurapa kushushikana, kusagadzikana kana kushaya hope.
• Kushandisa zvinodhaka kana doro zvisina kufanira.
• Metabolic disorders.
• Kushaikwa kwevhitamini.
• A tumarara, gomarara kana kuti bhenen inobata cerebellum.

Dominant hereditary ataxias inokonzerwa negene kubva kumubereki mumwe.

Semuyenzaniso:

• THEspinocerebellar ataxia. Kune anenge 36 akasiyana (yakasarudzwa SCA1 kune SCA30) yechirwere, inoratidzwa nemazera akasiyana ekutanga uye nhengo dzakasiyana dzakakanganiswa kuwedzera kune cerebellum (eg ziso).
• THEataxia episodic. Kune 7 marudzi episodic ataxias (yakasarudzwa EA1 kuEA7) inotaridza sekurwiswa kwakanyanya kunokanganisa kuenzanisa uye kurongeka.

Hereditary recessive ataxias inokonzerwa nejeni kubva kuvabereki vose.

Semuyenzaniso:

• THEFriedreich's ataxia.

Izvi zvakagarwa nhaka zvinofambira mberi neuromuscular chirwere chinokonzera kuderera kwekugadzirwa kwesimba mumuviri. Mitsipa nemasero emwoyo ndiwo anonyanya kukanganiswa. Vanhu vane kufamba kusina kujairika, kusagadzikana uye mumwe kusagadzikana kwekutaura, inooneka muuduku kana kuti ichiri kuyaruka. Izvi zvisizvo zvinotungamirira kukuchinja kwemapfupa, zvakadai sekumonya kwemusana (scoliosis), kukanganisa kwetsoka, pamwe nekuwedzera kwemoyo. MuEurope, munhu mumwe chete pavanhu makumi mashanu anofungidzirwa kuti ane chirwere ichi. MuFrance, kune vangangoita 1 varwere.

• THEataxia spastic Charlevoix-Saguenay (ARSACS).

Ichi chirwere chisingawanzogarwa nhaka chakanangana nevanhu vanobva kunzvimbo dzeSaguenay-Lac-St-Jean neCharlevoix muQuebec. Zvinoita kuti a kuderera kwemusana, inoperekedzwa nekukanganisa kunowedzera kune peripheral nerves. Vanhu vanosvika mazana maviri nemakumi mashanu vanobatwa nechirwere ichi munzvimbo dzakabatwa nechirwere ichi. Anenge 250 muvanhu makumi maviri nevaviri vanotakura geni reARSACS munzvimbo idzi.

• L 'ataxia telangiectasia kana Louis-Bar Syndrome.

Ichi chisingawanzo genetic chirwere chinokanganisa locomotion, ivo tsinga (dilation) uye rokuzvidzivirira. Chirwere chacho chinowanzoonekwa pazera remakore 1 kana 2. Kuwanda kwayo kunofungidzirwa kuve kwakatenderedza 1 mu40 kusvika ku000 vanozvarwa pasi rese.

Zvinogonawo dzimwe nguva kuitika kuti hapana mubereki anotambura nechirwere uye munyaya iyi hapana nhoroondo yemhuri yakajeka (kunyarara kushanduka).