Zvikonzero zvekusakendenga uye kushatirwa muchirwere cheAlzheimer zvinoburitswa

Vatsvagiri vepaIndiana University Chikoro cheMishonga (USA) kekutanga vakafumura mamorekuru ari pasi pezviratidzo zveurouropsychiatric izvo zvinowanzo tungamira kudzikira kwehungwaru muchirwere cheAlzheimer. Tiri kutaura pamusoro pekurasikirwa kwekukurudzira, kusava nehanya, kuzvidya mwoyo, kushanduka kwemafungiro kamwe kamwe uye kuwedzera kwekutsamwa.

Masayendisiti akatarisa pane nucleus accumbens, nharaunda yehuropi inoita basa rakakosha muhurongwa hwemubairo. Inobva ku nucleus accumbens kuti kuita kune ruzivo rwekukurudzira kunoenderana. 

Vatsvakurudzi vakaona kuti varwere veAlzheimer vane mareceptor mu nucleus accumbens inobvumira calcium kupinda neuroni. Kazhinji, hapafanirwe kuve nema receptors akadaro mu nucleus accumbens. Kuwanda kwecalcium kunotungamirira kurufu rwetsinga uye kurasikirwa kwekubatanidza synaptic pakati pavo, izvo zvinokonzeresa hunhu neuropsychiatric zviratidzo.

Kubva pane izvi, masayendisiti anoratidza kuti kuvharirwa kwakanangwa kwe calcium receptors mu nucleus accumbens kunogona kudzivirira kana kunonoka kutanga kwechirwere cheAlzheimer.

^{Kunobva: Molecular Psychiatry}