Aglan 15 - zviratidzo, contraindications, chipimo chemushonga, mhedzisiro

Proven content

Aglan 15, chinhu chinoshanda icho chinonzi meloxicam, ndeyeboka rezvisiri-steroidal anti-inflammatory drugs (NSAIDs). Iinewo analgesic uye antipyretic effect, uye inowanikwa pane zvinyorwa.

Aglan 15 - chii chinodhaka ichi?

Aglan 15 isiri-steroidal anti-inflammatory drug. Iinewo analgesic uye antipyretic effect. Chinhu chayo chinoshanda i meloxicam, iyo inhibisa basa re cyclooxygenases, kunyanya cyclooxygenase-2 (COX-2) uye cyclooxygenase-1 (COX-1).

Agalan 15 - chiratidzo chekushandisa

Kugadzirira kunoshandiswa kunyanya kurapwa kwevanhu vakwegura, vanhu vakakuvadzwa, vashandi vebhuruu-collar uye vaimbova vatambi. Zviratidzo zvekushandiswa kweAgalan 15 zvirwere zvakadai se:

1. rheumatoid arthritis chirwere chisingaperi. Inosanganisira nhengo uye majoini. Kana rheumatoid arthritis kurapwa ikasiyiwa isina kurapwa, kukuvadzwa kwemajoini uye mune dzimwe nguva kunyange kufa kunoguma. Chirwere ichi chinokonzerwa nehosha yemarunda, tendon, mapfupa uye cartilage. Chirwere ichi chinokonzerwawo nemajini, kusashanda kwesimba rekudzivirira uye dzimwe nguva zvakare kunetseka kwakanyanya.
2. ankylosing spondylitis chirwere chisingaperi chinoputika chemusana, zviratidzo zve kyphosis nekuremara. Nekudaro, iyo mamiriro anogona zvakare kukanganisa hudyu, bendekete, maziso, moyo nemapapu. Zvichida chikonzero chechirwere ndeye genetic, immunological, zvakatipoteredza uye zvirwere zvebhakitiriya. Zviratidzo zvekutanga zvechirwere marwadzo akaderera kumashure ayo anopenya kusvika kumagaro.
3. Osteoarthritis chimwe chezvirwere zvakajairika zvelocomotor system. Inokonzerwa nekukanganiswa kwe articular cartilage - zvose maererano nehutano uye huwandu. Zviratidzo zvechirwere marwadzo uye kuoma kwejoini, izvo zvinokanganisa mitsara yayo uye kuderedza kufamba kwayo. Mhedzisiro yacho kuremara uye kuderera kwehupenyu hwehupenyu.

Aglan 15 - chiito

Chinhu chinoshanda cheAglan 15, semamwe asiri-steroidal anti-inflammatory drugs, inhibits biosynthesis uye prostaglandins. Kusvetwa kwayo kwakakwana kunoitika mushure mejekiseni re intramuscular. Meloxicam inosungira kumapuroteni eplasma uye inopinda mu synovial fluid, iyo inosvika kune inenge hafu ye plasma.

Nhengo iyo inonyanya kuita basa rekugadzirisa zvinhu zvinoshanda zvemushonga chiropa. Melkosicam inobudiswa zvose muchiropa uye mutsvina, zvose muhuwandu hwakafanana. Inotorwa zvakanaka kubva mudumbu rekudya. Mushure mekutonga nemuromo, huwandu hwepamusoro muropa hunowanikwa mukati meawa 5-6 mushure mekutonga, uye kugadzikana mukati memazuva 3-5 ekushandisa kugadzirira.

Aglan 15 - contraindications

Aglan 15 haifanirwe kutorwa nevanhu vane:

1. hypersensitivity kune meloxicam,
2. hypersensitivity kune zvinhu zvakafanana nemeloxicam;
3. asthma kurwisa
4. polypy mhino,
5. angioedema,
6. mikoko mushure mekutora NSAIDs,
7. mikoko mushure mekutora acetylsalicylic acid;
8. hemostatic kusagadzikana,
9. kutora anticoagulants,
10. kubuda ropa mudumbu
11. chechitatu trimester pamuviri.

Contraindication pakutora Aglan 15 zvakare:

1. peptic ulcer chirwere - chinhu chinoshanda chekugadzirira hachifaniri kushandiswa nevanhu vane chirwere chechirwere chechirwere chinoshanda kana chekare. Kutadza kuita izvi kunogona kutsamwisa dumbu remudumbu kana duodenum, zvichikonzera kurwadziwa kwekupisa mudumbu kunopenya kubva pachipfuva kusvika paguvhu. Zvinokonzerwa neacid yemudumbu inosangana neronda kana ronda remudumbu. Kushandiswa kweAglan 15 munyaya iyi kunogona kuva nemigumisiro yakakomba yehutano.
2. Kukundikana kwakanyanya kwechiropa - kunoratidzwa nekuparara kamwe kamwe mukushanda kwechiropa. Inogona kuitika semugumisiro wehutachiona neHBV, HAV, HCV, nekuda kwehupfu hwezvinodhaka uye sekuita kwemuviri kune hepatic vein thrombosis kana zvirwere zve systemic. Kukundikana kwechiropa hakuwanzo kukurumidza kuongororwa sezvo kazhinji kusingarwadzi.
3. Kukundikana kwakanyanya kwerenal muvarwere vasiri kuita dialysis - chiratidzo chechirwere chacho kukanganisa kamwe kamwe kwechiropa chinoshanda. Zvadaro pane kuwedzera kweropa creatinine concentration. Murwere anotanga kubuda weti shoma, ane kurutsa, manyoka, apererwa nemvura uye anotsva. Kutadza kweitsvo kwakanyanya kunowanzoitika semhedzisiro yenjodzi dzakasiyana siyana, semuenzaniso hondo, kudengenyeka kwenyika. Zvikonzero zvayo zvinogona kuva zvirwere nenephritis. Mukuwedzera, inogonawo kukonzerwa ne-non-steroidal anti-inflammatory drugs uye mishonga yemishonga yemhando isina kunaka.
4. Kutadza kudzora kwakanyanya kusingadzoreki kwemoyo mamiriro ekuti moyo unopomba ropa shoma kune dzimwe nhengo. Nekuda kweizvozvo, nhengo dzemuviri hadzina oxygen uye hadzigone kushanda nemazvo. Chimiro ichi chinoitika nekukasira. Zvikonzero zvaro zvinowanzova zvirwere zvakasiyana-siyana zvehutano hwemwoyo, kazhinji ischemic chirwere cheropa.

Aglan 15 - chipimo chemushonga

Mushonga unopiwa sejekiseni. Chiyero chinokurudzirwa ndeye 7,5-15 mg / zuva. Mune zvirwere zvakadai se rheumatoid arthritis kana ankylosing spondylitis, iyo yakakurudzirwa dose ndeye 15 mg / zuva. Majekiseni anoiswa mukati memhasuru mukati mechikamu chepamusoro chegaro. Majekiseni anoshandiswa zvakachinjana - kureva kamwe kuruboshwe uye kamwe mugaro rekurudyi. Kune sciatica, mushonga unogona kuwedzera marwadzo panguva yekutanga doses.

Chiyero chemushonga chinoenderana nezera remurwere. Mapoka akakosha evarwere vakura, vanhu vane renal insufficiency, vanhu vane hepatic insufficiency uye vana. Maererano nezvinokurudzirwa nemugadziri, muyero wemushonga unogona kupiwa kune vakuru ndeye 7,5 mg; varwere vane mukana wekuita mhedzisiro vanogona kupihwa 7,5 mg pazuva.

Chiyero chevarwere vedialysis vane chirwere chakakomba chetsvo hachifanirwe kudarika hafu yeampoule. Uyezve, varwere vane simba renal insufficiency havafaniri kupiwa kugadzirira. Sezvineiwo, kana renal insufficiency iri pakati nepakati, dose haifaniri kuderedzwa. Chisarudzo pamusoro pehukuru hwedhesi uye kuchinja kunobvira mukukosha kwayo kunofanira kubvunzurudzwa nenyanzvi yakakodzera. Pamusoro pezvo, hapana zvidzidzo zvinosimbisa kuchengetedzwa uye kushanda kwekupa Aglan kuvana gumi nevashanu nevechiri kuyaruka vanosvika makore gumi nemasere.

Aglan 15 - mhedzisiro

Aglan 15 inogona kukonzera kuita kweganda. Varwere vanorapwa ne meloxicam vanogona kukura Stevens-Johnson syndrome. Pakave zvakare nemishumo ye epidermal necrolysis. Nokudaro, vasati vatanga kurapwa nekugadzirira, murwere anofanira kuziviswa kuti kuita kwakadaro kunogona kuitika. Zvakakosha kuwedzera kuti mukana weStevens-Johnson syndrome uye epidermal separation yakakura mukati memavhiki ekutanga ekurapa.

Aglan 15, kufanana nedzimwe NSAIDs, inogona kuwedzera serum transaminosis. Zvakare, inogona zvakare kushandura chiropa basa mamaki. Apo kuchinja kunokonzerwa nayo kunoratidza kuva kwenguva refu, ipapo mushonga unofanirwa kumiswa uye kuongororwa kwakakodzera kunoitwa. Migumisiro inogona kunyanya kunetsa kune vanhu vane immune system isina simba uye vanhu vane muviri wakareruka kuvaka.

Aglan 15 - zvidziviriro

Kushandiswa kweNSAIDs kunowedzera njodzi yekubuda ropa mudumbu, chirwere cheronda kana kuputika - iyo yakanyanya kuwanda yemushonga, kunowedzera mukana wekubuda ropa. Vanhu vari muboka iri renjodzi vanofanira kugara vachibvunza chiremba wavo nezve chero sarudzo maererano nekushandiswa kwemushonga. Iri boka revarwere rinowanzokurudzirwa kutora iyo yakaderera inogoneka dose yeAglan 15.

Kana paine mhedzisiro inoonekwa panguva yekurapa, bvunza chiremba nekukurumidza. Kuchenjerera kunofanira kuitwa muvarwere vari kutora mishonga pamwe chete iyo inogona kuwedzera njodzi yeronda kana kubuda ropa. oral corticosteroids, anticoagulants, selective serotonin reuptake inhibitors kana antiplatelet zvinodhaka.

Vanhu vane arterial hypertension vanofanirwa kurapwa kwakakosha panguva yekurapa nemushonga. Pane njodzi yekuti kutora dzimwe NSAIDs kunogona kuwedzera njodzi yekurwadziwa kwemoyo kana sitiroko, kunyanya muvashandisi venguva refu. Vanhu vanotambura nezvirwere zvakadai se:

1. Chirwere chekorona (coronary artery disease) - iyi ndiyo mamiriro ezvinhu umo mwoyo hauna kukwana kupiwa neokisijeni. Chikonzero chacho ndechekutetepa kwema coronary arteries, ayo anokonzera kupihwa kwezvinovaka muviri kumhasuru yemoyo. Chirwere checoronary artery kazhinji chinonzi atherosclerotic. Chirwere chemoyo chinonyanyozivikanwa munyika dzakabudirira zvikuru.
2. hypertension isingadzoreki - chikonzero chechirwere ndechekuwedzera kweropa remvura pamadziro emagetsi. Somugumisiro, kune kukanganisa kumidziyo uye nekudaro kune chirwere chemoyo. Kuwanda kweropa kunoenderana nehuwandu hweropa rinoputirwa mutsinga uye kushorwa kwemidziyo yeperipheral. Chirwere chacho chinogona kunge chisina zviratidzo kwenguva yakareba, uye zvimwe zvacho zvinosanganisira misoro isina musoro, dzungu uye kubuda ropa mumhino.
3. peripheral arterial disease - mamiriro ezvinhu anoita kuti tsinga dzako dziite shoma uye dzivhare, zvichiita kuti ropa riderere. Izvo zvinokonzerwa nekuvakwa kwemafuta plaque mutsinga dzako. Zviratidzo zvechirwere zvinosanganisira kuneta uye kupera simba mumakumbo, marwadzo emakumbo, kurira kwetsoka, kupera kwemaoko netsoka, ganda rinotonhora uye kuchinja kwemavara eganda.
4. cerebrovascular disease - iboka rezvirwere izvo chiratidzo chinokanganisa kuyerera kweropa kune dzimwe nzvimbo dzeuropi. Zvirwere izvi, semuenzaniso, sitiroko, subarachnoid hemorrhage, aneurysms yeuropi, chisingaperi cerebral atherosclerosis, cerebral thrombosis, cerebral embolism. Zvirwere zvinogona kuuraya. Zvinhu zvinobatsira pakuumbwa kwavo ndezvi: high blood pressure, high cholesterol uye kuwandisa.

Aglan 15 - kusangana nemamwe madhiragi

Kushandiswa pamwe chete kweAglan 15 nemamwe maNSAID kunogona kuita kuti gastrointestinal ulcer uye kubuda ropa. Hazvikurudzirwiwo kutora mishonga isiri-steroidal anti-inflammatory uye oral anticoagulants panguva imwe chete.

Aglan 15, kufanana nedzimwe NSAIDs, inogona kuderedza kushanda kwema diuretics uye antihypertensive mishonga. Kutyisidzira kuhutano, kunyanya kune vakwegura uye vanhu vane kukanganisa renal basa, ndiko kushandiswa panguva imwe chete kwe, semuenzaniso, ACE inhibitors uye vamiririri vanodzivisa cyclooxygenase. Varwere vanotora mishonga iyi vanofanira kunyanya kugara hydrated.

Kushandiswa panguva imwe chete kweAglan 15 nemishonga inorwisa BP kunokuvadzawo. Nekuda kweizvozvo, iyo antihypertensive drug beta-adrenergic blocker haishande. NSAIDs mune dzimwe nguva inowedzera nephrotoxicity yecyclosporine nekuda kwekuita kwavo kune renal prostaglandin. Vanhu vanotora mushonga vanofanira kugara vachitarisirwa nachiremba - izvi zvinonyanya kushanda kune vakwegura.