Chikamu chimwe muzvitatu chevarwere vakabatwa negomarara repahuro vane hutachiwana hwehuman papillomavirus (HPV), inonyanya kuenderana negomarara remuromo wechibereko, inodaro Journal of Clinical Oncology.
Utachiona hwehuman papillomavirus (HPV) ndehumwe hwakanyanya kuitika munyika. Utachiona hunotapurirwa kunyanya pabonde kuburikidza nekusangana kwakananga kwe mucous membranes yenhengo dzepabonde, asiwo ganda rakavapoteredza. Sangano reWorld Health Organization (WHO) rinoti vanhu vanosvika zvikamu makumi masere kubva muzana. Vanhu vanoita zvepabonde vanoita utachiona hweHPV pane imwe nguva muupenyu hwavo. Kune vakawanda vavo, ndezvenguva pfupi. Nekudaro, mune imwe muzana inova isingaperi, izvo zvinowedzera njodzi yekuva nemhando dzakasiyana dzekenza.
Pakati peanopfuura zana anozivikanwa subtypes (anonzi serotypes) ehuman papillomavirus (HPV), akati wandei ane carcinogenic. Kune kunyanya maviri madiki - HPV100 uye HPV16, ayo ane mutoro weanosvika makumi manomwe muzana. nyaya dzegomarara remuchibereko.
Nyanzvi dzeWHO dzinofungidzira kuti hutachiona hweHPV hunokonzera chikamu chinosvika zana kubva muzana. zviitiko zvegomarara remuchibereko, uye kuwedzera kwe100 muzana. rectal cancer kesi, 90 muzana zviitiko zvegomarara rekunze kwenhengo dzakavandika - kureva vulva, vagina uye urume, asiwo kune imwe muzana yemusoro nemutsipa kenza, kusanganisira 40% kenza yegomarara uye pharynx uye approx. 12 muzana. kenza dzemukanwa. Kune zvakare zvidzidzo zvinoratidza kubatanidzwa kwehutachiona mukukura kwegomarara rezamu, remapapu uye reprostate.
Zvidzidzo zvenguva pfupi yapfuura zvinoratidza kuwedzera kwechiitiko chegomarara rehuro uye laryngeal maererano nehutachiona hweHPV. Kusvika parizvino, kunwa doro zvisina kufanira uye kuputa zvave zvichionekwa sechinhu chakakosha chengozi kune aya magomarara. Masayendisiti anofungidzira kuti kuwedzera kwekubatanidzwa kweHPV mukugadzirwa kwekenza idzi kune hukama nerusununguko rwakakura rwepabonde uye mukurumbira wekusangana pabonde.
Kuedza hukama pakati peHPV nekenza yemamwe magomarara emusoro nemutsipa, masayendisiti kubva kuboka renyika dzakawanda vakaita ongororo yevarwere ve638 vanotambura navo, kusanganisira nekenza yemumuromo (180 varwere), kenza yeoropharynx (135 varwere) , kenza yepasi pharynx / larynx (247 varwere). Vakaongororawo varwere vane gomarara resophageal (300 vanhu). Kuenzanisa, 1600 vanhu vane hutano vakaedzwa. Vese vaive vatori vechikamu muongororo yenguva refu yeEuropean pahukama pakati pemararamiro nenjodzi yegomarara - European Prospective Investigation kupinda Cancer uye Nutrition.
Masampuli eropa akapihwa ese pakutanga kwechidzidzo ichi achiri mutano akaongororwa kuti aonekwe masoja ekudzivirira chirwere eHPV16 mapuroteni pamwe nemamwe mapillomavirus emudumbu akaita seHPV18, HPV31, HPV33, HPV45, HPV52, neHPV6 neHPV11 Chinonyanya kukonzera genital warts dzinonetsa (dzinonzi genital warts), uye hadziwanzokonzeresa gomarara remudumbu.
Sampuli dzegomarara dzaive paavhareji makore matanhatu, asi vamwe vaive vakatopfuura makore gumi vasati vaongororwa.
Zvakazoitika kuti vakawanda se35 muzana. Varwere vegomarara reOropharyngeal vakawanikwa vaine masoja ekudzivirira chirwere kuprotein yakakosha yeHPV 16, yakapfupikiswa seE6. Inodzima puroteni inokonzeresa kuvharidzira neoplastic process mumasero uye nekudaro inobatsira mukukura kwayo. Kuvapo kwemasoja ekudzivirira chirwere kuE6 protein muropa kunowanzoratidza kukura kwegomarara.
Kuenzanisa, muboka rekutonga chikamu chevanhu vane ma antibodies muropa chaiva 0.6%. Pakanga pasina hukama pakati pekuvapo kwavo uye mamwe mapundu emusoro nemutsipa akabatanidzwa muchidzidzo.
Vatsvagiri vakasimbisa kuti hukama pakati pekuvapo kweaya masoja ekudzivirira chirwere negomarara reoropharyngeal aivepo kunyangwe kune varwere vakatorwa sampu yeropa makore anopfuura gumi isati yaonekwa kenza.
Sezvineiwo, pakati pevarwere vane kenza oropharyngeal uye kuvapo anti-HPV16 antibodies, yakaderera muzana yevakafa nekuda kwezvikonzero zvakasiyana-siyana yakawanikwa pane pakati pevarwere vasina masoja ekudzivirira chirwere. Makore mashanu mushure mekuongororwa, 84 muzana vakanga vachiri vapenyu. vanhu kubva muboka rekutanga uye 58 muzana. chimwe chacho.
Izvi zvinoshamisa zvabuda zvinopa humwe humbowo hwekuti HPV16 chirwere chinogona kunge chiri chikonzero chakakosha chegomarara reoropharyngeal, anodaro munyori anoshanda pamwe Dr. Ruth Travis weYunivhesiti yeOxford.
Sara Hiom anobva kuCancer Research UK foundation akataura mubvunzurudzo neBBC kuti hutachiona hweHPV hwakapararira.
Kuita bonde zvisina njodzi kunogona kuderedza njodzi yekutapurirwa utachiona kana kutapurira HPV kune mumwe munhu, asi makondomu haakwanise kukudzivirira zvachose kubva kuhutachiona, akadaro. Zvinozivikanwa kuti hutachiwana huripo paganda munzvimbo yepabonde hunogonawo kuva chitubu chetachiona.
Hiom akasimbisa kuti hazvizivikanwe kana jekiseni riri kushandiswa pari zvino kudzivirira gomarara remuromo wechibereko muvasikana vechidiki (rimwe rawo rinotenderwa kuti vakomana vadzivise gomarara resikarudzi negomarara repenile) rinogona kuderedza njodzi yegomarara reoropharyngeal. Kana tsvagiridzo ichisimbisa izvi, zvichazoitika kuti inogona kushandiswa zvakanyanya mukudzivirira kweakaipa neoplasms. (PAP)
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