Bone marrow depression kuderera kwenhamba yemasero eropa. Inogona kuve nehanya nehuwandu hwemasero matsvuku eropa, masero machena eropa uye / kana maplatelet. Kuneta kwese, kushaya simba, zvirwere zvinodzokorora uye kubuda ropa kusina kujairika kunogona kuitika. Isu tinowanzo kutaura nezve idiopathic aplastic anemia nekuti mavambo ayo haazivikanwe muhuwandu hwakawanda hwezviitiko.

Tsanangudzo yeaplastic anemia

Bone marrow aplasia chirwere chemapfupa emapfupa, ndiko kuti, chirwere chinokanganisa nzvimbo iyo masero eropa anogadzirwa. Iyi synthesis inobatwa zvakasimba, izvo zvinotungamirira kuderera kwehuwandu hwemasero muropa.

Sechiyeuchidzo, kune marudzi akasiyana emasero eropa: masero matsvuku eropa (masero matsvuku eropa), masero machena eropa (leukocytes) uye maplatelet (thrombocytes). Kufanana nemasero ose, aya anovandudzwa nenzira yomuzvarirwo. Masero matsva eropa ari kuramba achigadzirwa nemwongo webhonzo kubva kumasero. Panyaya yeaplastic anemia, stem masero anonyangarika. 

Migumisiro yeaplastic anemia

Migumisiro yacho inogona kusiyana pamunhu nemunhu. Kuderera kwemasero eropa kunogona kuitika zvishoma nezvishoma kana kamwe kamwe, uye zvakanyanya kana zvishoma. Mukuwedzera, marudzi akasiyana-siyana emasero haasati abatwa nenzira imwechete.

Saka zvinokwanisika kusiyanisa:

• anemia, kuderera kwenhamba yemasero matsvuku eropa, ayo anoita basa guru mukutakura okisijeni mumuviri;
• leukopenia, kudonha kwenhamba yemasero machena eropa anobatanidzwa mukudzivirira kwemuviri;
• thrombocytopenia, kudonha kwehuwandu hweplatelet muropa rinozivikanwa kuti rinokosha muchiitiko chekubatana kana chiitiko chekukuvara.

Zvinokonzera aplastic kupererwa neropa

Muzviitiko zvakawanda, mavambo eiyi pathology yemapfupa emapfupa haazivikanwi. Isu tinotaura nezve idiopathic aplastic anemia.

Zvakadaro, tsvagiridzo inoratidza kuti aplastic anemia ndiyo mhedzisiro ye autoimmune phenomenon. Nepo immune system ichiwanzoparadza utachiona, inorwisa masero ane hutano akakosha kuti muviri ushande nemazvo. Panyaya yeaplastic anemia, immune system inoparadza stem masero anodiwa pakugadzirwa kwemasero matsva eropa.

Kuongororwa kweaplastic anemia

Kuongororwa kunotanga kubva pahuwandu hweropa rakazara (CBC), kana kuti ropa rakazara. Kuongororwa kweropa kunotorwa kuongorora mazinga emhando dzakasiyana dzemasero (masero matsvuku eropa, masero machena eropa, maplatelet).

Kana mazinga acho asina kujairika, mimwe miedzo inogona kuitwa kusimbisa kuongororwa kweaplastic anemia. Semuyenzaniso :

• myelogram, muedzo unosanganisira kubvisa chikamu chepfupa chekuongorora;
• a bone marrow biopsy, bvunzo inobvisa chikamu chemwongo nebhonzo.

Vanhu vanobatwa neaplastic anemia

Vanhukadzi vese vari kubatwa nechirwere ichi. Inogonawo kuitika chero pazera. Zvakadaro mapeji maviri epamusoro akaonekwa ari pakati pemakore makumi maviri nemakumi maviri nemashanu uye mushure memakore makumi mashanu.

Iyi pathology inoramba isingawanzo. MuEurope neUnited States, chiitiko chayo (nhamba yezviitiko zvitsva pagore) ndeye 1 pa500 vanhu uye kuwanda kwayo (nhamba yezvidzidzo zvakabatwa nechirwere muhuwandu hwakapihwa panguva yakatarwa) ndeye 000 mu1 yega yega.

Iyi pathology yemapfupa emapfupa inogona kuonekwa nekuderera kwehuwandu hweropa remasero matsvuku eropa (anemia), masero machena eropa (leukopenia) uye / kana maplatelet (thrombocytopenia). Zviratidzo zveaplastic anemia zvinoenderana nemhando dzemasero eropa akabatwa.

Generalized kuneta uye kushaya simba kwakabatana neanemia

Anemia inoratidzwa nekushomeka kwemasero matsvuku eropa. Inogona kukonzera zviratidzo zvakadai se:

• kupenya kweganda uye mucous membranes;
• kuneta;
• dzungu;
• mweya wekufema;
• palpitations pakushanda nesimba.

Ngozi inotapukira ye leukopenia

Leukopenia inoguma nekudonha kwehuwandu hwemasero machena eropa. Muviri unorasikirwa nekukwanisa kuzvidzivirira kubva kukurwisa kubva kuhutachiona. Zvirwere zvinodzokororwa zvinogona kuitika pamatanho akasiyana emuviri.

Kubuda ropa nekuda kwe thrombocytopenia

Thrombocytopenia, kana kuderera kwenhamba yeplatelet, inokanganisa chiitiko che coagulation. Kubuda ropa kwezviyero zvakasiyana-siyana zvekusimba kunogona kuonekwa. Vanogona kukonzera:

• kubuda ropa mumhino nemazino;
• mavanga nemavanga anoonekwa pasina chikonzero.

Kutarisira kweaplastic anemia kunoenderana nekushanduka kwayo. Kunyange zvazvo kutarisira kurapwa kwakapfava dzimwe nguva kuchigona kukwana, kurapwa kunodiwa muzviitiko zvizhinji.

Mune yazvino mamiriro eruzivo, nzira mbiri dzekurapa dzinogona kutariswa kurapa aplastic anemia:

• kurapwa kwe immunosuppressive kunobva pamishonga inokwanisa kuvharidzira immune system kuitira kudzikamisa, kana kumisa, kuparadzwa kwe stem cell;
• kuisirwa mwongo, izvo zvinosanganisira kutsiva mwongo unorwara nemwongo webhonzo une hutano unotorwa kubva kune anozvidavirira anopa.

Nepo kuisirwa mwongo pari zvino kuri iko kurapwa kwakanyanya kweaplastic anemia, kuvhiya uku kunongotariswa mune mamwe mamiriro. Iyo inorema kurapa iyo isiri isina njodzi yepostoperative matambudziko. Kazhinji, kuisirwa kwemapfupa emapfupa kunochengeterwa varwere vari pasi pemakore makumi mana ezera vane maitiro akaoma emapfupa aplasia.

Mishonga inotsigira inogona kupihwa kugadzirisa zviratidzo zveaplastic anemia. Semuyenzaniso :

• mishonga inorwisa mabhakitiriya kudzivirira kana kurapa zvimwe zvirwere;
• kuisirwa masero matsvuku eropa kana anemia;
• Kuwedzerwa kweplatelet mu thrombocytopenia.

Kusvika iye zvino, hapana nzira yekudzivirira yakaonekwa. Muzviitiko zvakawanda, chikonzero cheaplastic anemia hachizivikanwi.