Le Gougerot-Sjögren syndrome (taura sjeu-greunne), inova chikamu cheiyo yakaoma syndromes, isingaperi mamiriro e autoimmune mabviro, ie akabatana nekuita kwe immune system kurwisa zvimwe zvikamu zvemuviri, mune iyi kesi exocrine glands, inovanza zvinwiwa mukati. ganda kana mucous membranes.

Kuwanwa kwayo kunotangira muna 1933, naD^r Henrik Sjögren, chiremba wemaziso wekuSweden.

Kuratidzira kwaro kwakabatana nekupinzwa kwemamwe maglands ne lymphocytes zvichikonzera kuderera kwekuvanzika kwavo. Iyo salivary glands yemuromo uye mazamu emarara ndiwo anonyanya kukanganiswa, anokonzera "dry syndrome". Isu tinogona zvakare kuona kudzikira kwedikita, sebum asiwo kupinda mukati uye kuzvimba mune dzimwe nhengo dzakadai semapapu, itsvo, majoini kana midziyo midiki.

Gougerot-Sjögren syndrome chirwere chisingawanzobata pasi pemunhu mumwe chete muvakuru gumi. Vakadzi vanobatwa neka 10 kupfuura varume. Inowanzoitika pazera remakore gumi asi inogona kuitika kare pazera remakore 000 ne10. 

Types

Chirwere chinogona kuzviratidza nenzira mbiri:

• Primary. Chirwere ichi chinoonekwa chiri chega. Izvi ndizvo zvakaitika 1 nguva mu 2. Inenge 93% yevaya vanobatwa vari vakadzi, uye zviratidzo zvinowanzoonekwa pazera remakore makumi mashanu;
• Secondary. Chirwere chacho chinosanganiswa nechimwe chirwere che autoimmune, chinowanzonzi rheumatoid arthritis.

Zvinokonzera

Chikonzero che Gougerot-Sjögren syndrome hazvizivikanwe. Zvisinei, chirwere chinokonzerwa ne autoimmune reaction. Chikonzero nei rokuzvidzivirira yemuviri inosvika pakusashanda zvakanaka uye kurwisa matissue ayo pachawo ichiri nebulous. Mafungiro akawanda ari pasi pekudzidza. Maererano nevatsvakurudzi, zvingangoita kuti kutanga kwechirwere ichi kunoda zvose genetic kufungidzira nekusvika kwe zvinokonzera zvinhu (utachiona hwehutachiona, kuchinja kwehomoni, kushungurudzika, nezvimwewo).

The zviratidzo

Muchikamu che2/3 chezviitiko zvinoratidzwa zvakabatana nekubatanidzwa kwezvipembenene zveexocrine zvinosanganiswa nekubatanidzwa kweimwe nhengo (iyi inonzi chirwere chemaitiro)

Meso akaoma uye muromo zvinowanzotanga kuitika. Zvisinei, dzinoonekwa gare gare kune vanhu vanotova nearthritis. 

Mumaziso, kuoma kunogona kukonzera kupisa kana kuchenesa. Maziso anowanzo kunamatira pamwe chete mangwanani, uye maziso anonyanya kunzwa kune chiedza.

Muromo wakaoma unoita kuti kutaura, kutsenga uye kumedza kuve kwakaoma. 

Tinogonawo kuona chikosoro chinoramba chakaoma, kurwadziwa kwemajoini, kurwadziwa kwemhasuru, kuneta

Iyo sicca syndrome inogona kuomeswa pamwero weocular ne blepharitis kana keratitis uye pamwero wemukanwa nekukuvadzwa kwemazino, cavities, kufamba kwemazino, canker maronda, muromo hutachiona hwechipiri kunyanya ne mycoses. Mumwe anogona kuona hypertrophy yezvipembenene zveparotid, zvishoma kana kwete.

Iyo yekuwedzera glandular kuratidzwa kunobata majoini (imwe mu2), Raynaud's syndrome (minwe ichiva chena mukupindura kutonhora). Kumwe kurwiswa kwakanyanya asi kusingawanzo, papulmonary, renal, cutaneous kana peripheral nerves level. 

Kuneta kwakajairika, uye kunoperekedzwa nekurwadziwa kwakapararira.

chirwere

Kuongororwa kwakaoma nekuti munhu anenge asina zviratidzo zvese uye izvi zvinogona kunge zvine chekuita nezvimwe zvirwere kana kutora mishonga.

Kuongororwa kwakasiyana-siyana kwakakosha: kutsvaga masoja ekudzivirira chirwere ari muropa (anti-SS-A, anti-SS-B masoja ekudzivirira chirwere), ongororo yekugadzirwa kwematumbu emuromo uchishandisa sefa bepa (Schirmer's test), kucherechedzwa kwe membrane yakatetepa. iyo inovhara ziso nekusviba nerose bengal uye bvunzo yemate yekuongorora kuoma kwemuromo uye kuratidzwa kwe lymphocytic nodules pane saliva biopsy; inoitwa mumuromo salivary glands, ichi chiito hachina hasha uye hachirwadzi. Kuongororwa kunobva pakusanganiswa kwehuwandu hwezviratidzo zvekliniki uye zvehupenyu. 

Chiremba anogona zvakare kukurudzira kuongororwa kune dzimwe nzvimbo dzechirwere kana mamwe autoimmune pathologies.

Panguva yekuongororwa, chiremba anobvunza murwere nezvehutano hwake huzhinji, marudzi emishonga yaari kutora, uyewo nezvekudya uye chiyero chemvura nezvimwe zvinwiwa zvinodyiwa zuva nezuva.