Inotsanangurwa nekuratidzwa kwezviratidzo zvitsva zvisingafadzi mushure mekutora zvinodhaka, zvinodhaka iatrogenism inoumba dambudziko rehutano hweveruzhinji, kunyanya kune vakwegura uye muvana. Chero mhedzisiro isingatarisirwe inofanirwa kutaurwa nemutarisiri kuPharmacovigilance Center. 

Zvirwere zveIatrogenic ndiyo seti yezviratidzo zvisingadiwe zvinoitika pamwe chete nezviratidzo zvechirwere chiri kurapwa semugumisiro wekurapa zvinodhaka. Kutaura zvazviri, mishonga inobudirira mukurwisana nezvimwe zvirwere inogona kukonzera migumisiro isingafadzi, inosiyana pamunhu nomunhu, uye inogona kukanganisa utano hwomurwere ari kurapwa. Vanogona kutora zvakasiyana-siyana sekuputika kweganda nekuda kwezvinodhaka zvinodhaka, kuwedzera kweropa reropa kana tsaona yekugaya hemorrhagic.

Iyi mhedzisiro inowanzoitika uye mazhinji acho akanyorwa pamirayiridzo yemishonga inotarwa. Nzvimbo yedunhu re pharmacovigilance inounganidza mishumo yese kubva kuvashandi vehutano uye inovandudzwa nguva nenguva. Chinangwa chedhatabhesi iyi ndechekudzivirira njodzi idzi dzezvirwere zveiatrogenic, izvo zvinogara zvisingatarisirwi, uye nekudaro zvinotungamira kune shanduko yekurapa kana kugadzirisa (kuderedza uye kuparadzaniswa kwemadosi, kutora mushonga pakati pekudya. nemumwe mushonga unodzivirira…).

Vakwegura ndivo vanonyanya kubatwa nezvirwere zve iatrogenic, nokuti vanowanzova polymedicated (mishonga yakawanda inofanira kutorwa panguva imwe chete) uye inonyanya kunetseka. Izvi zvinokonzerwa nekaviri zvinowanzoitika mushure memakore 65 uye 20% yemigumisiro iyi inotungamirira kuchipatara.

Zvikonzero zvezvirwere zveiatrogenic zvakawanda:

• Overdose: kune njodzi yekuwedzeredza muchiitiko chekusadzora kutorwa kwezvinodhaka nekuda kwekusagadzikana kwepfungwa (kunetseka kwepfungwa) kunowanikwa kune vakwegura.
• Allergy kana kusashivirira: kune mamwe madhiragi akadai semaantibiotics, anti-inflammatory drugs, pain-relieving drugs (analgesics), chemotherapy, contraception, mamwe mafuta ekuzora, nezvimwewo. Aya allergies uye kusashivirira kunoramba kwakasiyana kubva kune mumwe munhu kuenda kune mumwe.
• Kunonoka kubviswa: kune zvakare njodzi yekudzikisa nzira dzekubvisa mamorekuru ezvinodhaka nechiropa kana itsvo, zvichikonzera kuwandisa kwezvinodhaka mumuviri.
• Kudyidzana kwezvinodhaka: Panogona kunge paine kusangana kwezvinodhaka pakati pemishonga miviri kana kupfuura inotorwa panguva imwe chete.
• Kugadziriswa kwemasabolism: nemimwe mishonga yakadai sema diuretics, laxatives, marapirwo ethyroid gland, nezvimwe.
• Kuzvirapa: izvo zvinokanganisa kurapwa kwakatemwa kana kusateera zvakanaka kumishonga.
• Mishonga isina kukodzera muvana kana vakwegura, zvichienderana nezera uye uremu.

Izvi zvinokonzeresa zviri pamavambo emushonga iatrogenism iyo inogona kazhinji kugadziriswa, asi iyo zvakare dzimwe nguva inotungamira kune dzakakomba tsaona iatrogenic.

Kuongororwa kwezvirwere zveiatrogenic uku kunoitwa kana zviratidzo zvichionekwa zvisingaenderane nechirwere chiri kurapwa. Dzungu, kudonha, kupera simba, kuneta kwakanyanya, manyoka, kuvimbiswa, dzimwe nguva kurutsa kweropa etc. Saka zviratidzo zvakawanda zvinofanira kunyevera murwere uye chiremba. 

Kubvunzurudza, kuongororwa kwekiriniki, mishonga inotorwa, kunyanya kana ichangoburwa, inotungamira kuongororwa uye ongororo dzekuwedzera dzinofanirwa kuitwa. Kumisa mushonga unofungidzirwa kuti ndiro danho rekutanga kutora.

Kana kuregera uku kuchiteverwa nekuvandudzwa kana kutonyangarika kwezviratidzo zvezvirwere zveiatrogenic, kuongororwa kunoitwa nechirwere chekurapa (kurega kurapwa). Izvo zvinozove zvakakodzera kunyora pasi mushonga unokonzera iyi side effect uye urege kuiraira zvakare. Imwe nzira ichafanirwa kuwanikwa.

• Kuvhiringidzika uye kusagadzikana kwepfungwa kunotevera kunyorerwa kwe diuretics iyo inosimudzira kuitika kwekudonha kwe sodium muropa (hyponatremia) uye kupera simba;
• Kubuda ropa mudumbu mushure mekutora anti-inflammatory drugs zvinoratidza chironda kana kunyange chironda chekudya;
• Rash, kuoma kwekufema uye kuzvimba kwechiso mushure mekutora mishonga inorwisa mabhakitiriya inoratidza kusawirirana kune iyi antibiotic;
• Malaise inotevera kubayiwa uye edema panzvimbo yejekiseni nekuda kwekusawirirana kwejekiseni;
• Oral kana gynecological mycosis inotevera antibiotic therapy, kwakabva kune kusaenzana kwemukanwa kana gynecological flora inotevera kurapwa.

Kurapwa kwemaside effects ekurapa kunowanzobatanidza kumisa kurapwa uye kutsvaga imwe nzira yekurapa. Asi zvinogona zvakare kuve kutarisira iyi mhedzisiro nekunyora mumwe mushonga wakadai senge anti-ulcer paunenge uchiraira anti-inflammatory drugs kana antimycotics panguva yekurapa maantibiotic.

Dzimwe nguva, zvichave zvakakwana kugadzirisa kusaenzana kunokonzerwa nemushonga, sekupa sodium kana potasium pakaitika dambudziko reropa (hyponatremia kana hypokalemia). 

A laxative yakapfava inogonawo kurongerwa pamberi pekuvhara mushure mekurapwa kwezvinodhaka kana chekufambisa chekufambisa kana paine manyoka. 

Chikafu chinogonawo kuiswa panzvimbo (yakaderera-munyu kudya, bhanana kune mupiro we potassium, kudya kwakaderera mumafuta akazara muchiitiko chekuwedzera kwecholesterol, nezvimwewo). 

Pakupedzisira, kurapwa kwekugadzirisa huwandu hweBP kunogona kurongerwa nekutarisa nguva dzose.