Iyo intestinal flora, inonziwo intestinal microflora kana intestinal microbiota, iboka rezvipembenene zvinogara mumatumbo. Non-pathogenic, tupukanana idzi dzinoita basa rakakosha mukugaya nekudzivirira kwemuviri. Sezvo zvakadaro, kusaenzana kwemaruva emukati kunogona kuva nemigumisiro inokuvadza.

Chii chinonzi intestinal flora kana gut microbiota?

Iyo intestinal flora, inonziwo intestinal microbiota, inomiririra seti yema microorganisms aripo mumatumbo. Aya ma microorganisms anonzi ane commensal, kureva kuti anogara maari symbiosis nemuviri wemunhu. Izvo hazvisi-pathogenic uye zvinobatsira mukushanda kwakakodzera kwemuviri.

Chii chinonzi intestinal microbiota?

Huru hwemudumbu hwaimbonzi intestinal bacterial flora nekuti ongororo dzakaratidza kuti yaisanganisira mabhakitiriya chete. Nekuda kwekufambira mberi kwesainzi, zvave kucherechedzwa kuti maruva emukati ane akawanda ma microorganisms anosanganisira:

• mhando dzakasiyana dzebhakitiriya ;
• ma virus ;
• mbiriso ;
• Mushroom;
• protozoa.

Basa reiyo intestinal microbiota mukufamba

Ongororo dzinoverengeka dzakasimbisa basa rakakosha remaruva emudumbu mukufambisa kwekudya. Kusaenzana mu intestinal microbiota inogona kunge iri chikonzero chekusagadzikana kwekudya.

Basa remaruva emukati mukugaya

Iyo intestinal flora inobatsira kugayiwa kwechikafu chakadyiwa, nekutora chikamu kunyanya mu:

• kushatiswa kwezvimwe zvinosara zvekudya kusanganisira mamwe mashizha emiriwo;
• hydrolysis yezvokudya lipids ;
• kuparara kwemamwe mapuroteni ;
• kusanganiswa kwezvikafu ;
• kuumbwa kwemamwe mavhitaminzi.

Kukosha kwemaruva emukati ekudzivirira kwehupenyu

Iyo intestinal microbiota inotora chikamu mukudzivirira kwemuviri. Iwo ma microorganisms emudumbu flora anoita kunyanya ku:

• kudzivirira kuiswa kwezvimwe zvirwere ;
• kuderedza kukura kwehutachiona ;
• kuwedzera immune system.

Mamwe mabasa angangove ari pasi pekudzidza kune intestinal flora

Ongororo dzinoverengeka dzinoratidza kuti kune zvakare kudyidzana pakati pehuropi uye intestinal microbiota. Kusaenzana kwemaruva emudumbu kunogona kunyanya kukanganisa ruzivo rwunoendeswa kunheyo yepakati.

Chii chinonzi dysbiosis

Dysbiosis inoenderana nea ura hwepamuviri kusaenzana. Izvi zvinogona kuratidzwa kunyanya ne:

• kusaenzana pakati pemamwe ma microorganisms, kunyanya pakati pepro-inflammatory agents uye anti-inflammatory agents;
• hukuru hwemamwe ma microorganisms zvakadai se enterobacteria kana fusobacteria;
• kupera kana kusavapo kwemamwe ma microorganisms zvakadai semabhakitiriya Faecalibacterium prausnitzii.

Ndeipi njodzi yezvinetso?

Tsvagiridzo pamusoro pemaruva emudumbu inoratidza kuti dysbiosis inogona kubatanidzwa mukukura kwezvimwe zvirwere zvinosanganisira:

• chirwere chisingaperi chinokonzera chirwere (IBD), zvakadai seCrohn's disease kana ulcerative colitis, iyo inoratidzirwa nekusakwana kwekudzivirira muviri mukati mematumbo;
• kusagadzikana kwemagetsi, zvakadai sechirwere cheshuga cherudzi rwechipiri uye kufutisa, izvo zvinokanganisa mashandiro anoita muviri;
• le kenza yakajeka, apo bundu rinokura mukoloni;
• zvimwe zvirwere zvetsinga, nekuda kwekubatana pakati pegut microbiota neuropi.

Ndezvipi zvinokonzerwa nedysbiosis?

Kusaenzana kwemaruva emudumbu kunogona kufarirwa nezvimwe zvinhu zvakaita se:

• kudya kwakashata;
• kutora mimwe mishonga;
• kunetseka.

Matanho ekudzivirira ekuchengetedza maruva emukati

Zvinokwanisika kudzivirira dysbiosis nekudzikamisa zvinhu zvine njodzi. Nokuda kweizvi, zvinodikanwa kutora kudya kwakanaka uye kwakadzikama, kudzidzira muviri nguva dzose uye kuderedza zvinhu zvekunetseka uye kufunganya.

Nutritional supplementation kudzorera maruva emukati

Kushandiswa kwezvokudya zvinowedzera zvinowanzokurudzirwa kudzorera maruva emukati. Chiyero cheiyo intestinal microbiota inogona kuchengetedzwa nekuda kwe:

• probiotics, izvo zvipenyu zvipenyu zvinobatsira pakuenzanisa kwemaruva emukati;
• prebiotics, izvo zvinhu zvinokurudzira kukura nekushanda kwebhakitiriya mumaruva emukati;
• symbiotics, ayo ari musanganiswa we prebiotics uye probiotics.

Faecal microbial transplantation

Muzviitiko zvakakomba, kuisirwa kwemamwe ma microorganisms emukati memaruva anogona kutariswa.

Preliminary bvunzo: kuongororwa kwemamwe mamaki

Kuongororwa kwemaruva emukati kunowanzokurudzirwa nekusava nechokwadi panguva ye kuongorora mumuviri. Muchiitiko chekufungira panguva yekuongororwa uku, nyanzvi yehutano inogona kukumbira kumwe kuongororwa. The kuyerwa kwezvimwe zviratidzo zvebhayoloji inogona kunyanya kuitwa. Kuvepo kwemamwe macherechedzo ekuzvimba anogona semuenzaniso kutsvakwa kusimbisa kukura kwechirwere chechirwere chechirwere chechirwere (IBD).

Coproculture: kuongororwa kwemaruva ari muchitsiko

Coproculture est a bacteriological kuongororwa kwechigaro. Kunyangwe ongororo iyi isingapi kuumbwa chaiko kwemaruva emudumbu, tsika yechituru inopa ruzivo rwakakosha kutungamira kana kusimbisa kuongororwa.

Iyi bacteriological analysis inogona kubatanidzwa ne parasitological kuongorora kwechigaro (EPS) kutarisa kuvapo kwezvipembenene.

Endosco? Pie digestive: invasive kuongororwa kwemaruva emukati

Digestive endoscopy, inonziwo digestive fibroscopy, inogona:

• fungidzira mukati megumbo rekudya kuziva kuvapo kwezvironda;
• kuita biopsy kuongorora matishu uye kuumbwa kwemaruva emukati.

Kufambira mberi kune imwe nzira yekuongorora isingadhuri?

Kana endoscopy iri invasive yekuongorora nzira, zvingangove zvichikwanisika kuita ongororo yematumbo emudumbu nenzira yakafanana neyekuongorora ropa. Izvi zvinogona kuitwa kuburikidza nekushandiswa kweDNA microarrays.

Kupfuma kwemaruva emukati

Maererano nevatsvakurudzi, kune ma microorganisms ari pakati petiririyoni nemazana ezviuru zvemazana mumatumbo. Saka akawandisa zvakapetwa kaviri kusvika kagumi pane masero ese ari mumuviri wemunhu.

Iyo yakaoma uye yakasarudzika gut microbiota

Iyo gut microbiota yakaoma uye yakasarudzika ecosystem. Nemhando dzinoda kusvika 200 dzakasiyana dzema microorganisms, kuumbwa kwayo chaiko kunoenderana nemunhu wega wega. Iyo intestinal flora inogadzirwa kubva pakuzvarwa uye inoshanduka nekufamba kwemakore zvichienderana nezvinhu zvakasiyana zvinosanganisira genetics, chikafu uye nharaunda.

Tarisiro dzinovimbisa

Basa rinoitwa pamaruva emudumbu rinovhura tarisiro yekurapa inovimbisa. Kuongororwa kwakadzama kwemaruva emudumbu kunogona kutungamira mukugadzirwa kwemishonga mitsva, iyo inogona kuve yakasarudzika maererano nechimiro chemukati memunhu wega wega.