Chikonzero chikuru pane zvosechisingaperi itsvo kutadza chirwere cheshuga, chingava chorudzi 1 kana 2. Izvi zvinokonzerwa nokuti chirwere cheshuga chinokuvadza tsinga duku dzeropa, kusanganisira dziri mukati meitsvo. Kazhinji, zvirwere zvinokonzeresa matambudziko emwoyo zvakare zvine njodzi yechirwere cheitsvo. Kuchembera, kukwira kweropa, kufutisa, chirwere cheshuga, kuputa uye kuderera kweHDL cholesterol ("yakanaka cholesterol")¹. Zvimwe zvinokonzera njodzi zvinogona kukonzera chirwere cheitsvo chisingaperi, kusanganisira zvinotevera:

• Pyelonephritis (utachiona hweitsvo);
• Polycystic itsvo chirwere;
• Autoimmune zvirwere, zvakadai se systemic lupus erythematosus;

• Kuvharwa kweurinary turakiti (sezvakaita mune yakawedzera prostate);
• Kushandiswa kwezvinodhaka zvakagadziriswa neitsvo, senge mamwe madhiragi ekenza chemotherapy.