Iko kusunganidzwa kweuric acid kunogona kutsanangurwa muropa kana mumurini. Kuwedzeredza, chinonyanya chiratidzo chegout, kunyanya kunwa doro kana kukundikana kwetsvo.

Uric acid iri dongo yemuviri. Kunyanya, ndicho chigadzirwa chekupedzisira chekubuda mamorekuru anonzi nucleic acids uye purines.

Kazhinji, yakawanda yeuric acid mumuviri wemunhu inonyungudika muropa uye inopinda muitsvo dzekupedza weti. Asi mune zvimwe zviitiko, muviri unoburitsa yakawandisa uric acid kana kutadza kubvisa yakakwana yacho. Aya mamiriro anogona kuve chikonzero cheakasiyana kusagadzikana.

Uric acid iri mugumo wechigadzirwa wekushatiswa kwe kutsvedza, mwero wayo unosiyana zvichienderana nezvinowanikwa mu purine mumuviri. Uye zvinoitika kuti purines inowanikwa kunyanya muchikafu. 

Zvimwe zvezvikafu zvine ma purine ekudzivirira ndeizvi:

• anchovies, herring, mackerel, sardines, shrimps, nezvimwe;
• chiropa, moyo, huropi, itsvo, chingwa chinotapira, nezvimwe;
• pizi, bhinzi dzakaoma, nezvimwe.

Iko kunwa kwedoro, uye kunyanya doro, hakukurudzirwe kana iwe uchida kudzikisa yako uric acid.

Pane zvinopesana, pakati pezvakabvumidzwa chikafu chakaderera mu purine, tinogona kutaura:

• tii, kofi, zvinwiwa;
• michero nemiriwo;
• mazai;
• chingwa nezviyo;
• chizi uye kazhinji zvigadzirwa zvemukaka

Nei uchiric acid bvunzo?

Chiremba anorayira kuongororwa kweropa (kunodaidzwa kuti uricemia) uye / kana kuti weti yeurinary uric acid yeku:

• tsvaga gout;
• ongorora mashandiro ari kuita itsvo;
• inogonawo kukumbirwa kana uine pamuviri;
• kana mune vanhu vakafutisa.

Ziva kuti kuongororwa kwehuwandu hweuric acid mumurini kuchaitawo kuti zvive nyore kunzwisisa mavambo ehuremu hweuric acid muropa.

Muropa, kukosha kweuric acid kuri pakati pe35 uye 70 mg / L.

Yakakwira yakakwira uric acid muropa inonzi hyperuricemia uye inogona kukonzerwa nekuwedzeredza kweuric acid mumuviri kana nekuderera mukubviswa kwayo neitsvo. Nekudaro, yakakwira uric acid muropa inogona kuve chiratidzo che:

• gout (ichi ndicho chikonzero chikuru chekuwedzera kweiyo uric acid muropa);
• kuwandisa kwekudzikiswa kwemapuroteni echinhu chinoitika, semuenzaniso, panguva yekemotherapy, leukemia kana kunyange lymphoma;
• kudhakwa;
• kunyanyisa kurovedza muviri;
• kuvapo itsvo matombo;
• kukurumidza kurasikirwa uremu;
• chirwere cheshuga;
• chikafu chakazara mu purine;
• preeclampsia panguva yekuzvitakura;
• kana kukundikana kweitsvo.

Pane kupokana, zvinokwanisika kuti iro ropa uric acid mwero wakadzikira pane zvakajairwa, asi ichi chiitiko chisingaenzanisike kupfuura mamiriro ezvinhu ayo anopedzisira ave pamusoro.

Nekudaro, uric acid mazinga ari pazasi akajairwa tsika anogona kunge aine hukama ne:

• kudya kwakaderera-purine;
• Chirwere chaWilson (chirwere chemajini umo ndarira inovaka mumuviri);
• itsvo (senge Fanconi syndrome) kana kukuvara kwechiropa;
• kana kunyatso sangana nemakemikari ane chepfu (lead).

Mune weti, iyo yakajairika kukosha kweuric acid iri pakati pe250 uye 750 mg / 24 maawa.

Ziva kuti zvakajairwa tsika dzinogona kusiyana zvishoma zvichienderana nemarabhoritari anoita ongororo.

Inobata 5 kusvika 15% yevagari, yakajairika biochemical kusagadzikana, zvichikonzerwa nekuwedzeredza kweuric acid uye / kana kudzora kutsvagisa renal. Iyo inowanzo kukura isingarwadzi uye nekudaro haiwanzo kuongororwa pakarepo.

High uric acid mazinga anogona kutsanangurwa ne:

Idiopathic kana yekutanga hyperuricemia

Ivo vanomiririra yakawanda kwazvo kesi. Hereditary predispositions inowanikwa mu30% yezvidzidzo, asi zvinowanzo kuve zvine chekuita nekufutisa, kudya zvakanyanya, kuwedzerwa kweropa, kudhakwa nedoro, chirwere cheshuga uye hypertriglyceridemia.

Kazhinji enzyme kusagadzikana

Ivo vanowanikwa kunyanya muVon Gierke chirwere uye chirwere cheLesch-Nyhan. Aya enzymatic abnormalities ane hunyanzvi hwekukonzeresa kurwiswa kwegout kutanga kwazvo, kureva mumakore ekutanga makumi maviri ehupenyu.

Hyperuricemia yechipiri kune chirwere kana kurapwa kwemishonga.

Aya hyperuricemia anogona kunge ari nekuda kwe:

- kushomeka kwekubviswa kweiyo uric acid. Iyi ndiyo mamiriro ekukundikana kweitsvo, asi zvakare nekuda kwemamwe madhiragi (diuretics, asiwo marapa uye mamwe ekurwisa TB.

- kuwedzera mukuderera kweiyo nucleic acids. Tinozviona izvi muzvirwere zveropa (leukemia, hemopathies, hemolytic anemia, yakazara psoriasis), uye nemhedzisiro yemamwe kenza chemotherapies.

Migumisiro ye hyperuricemia

Hyperuricemia inogona kukonzera mhando mbiri dzematambudziko:

• Gout inokonzeresa kupisa-mhando marwadzo akabatana.

Kana ma microcrystals euric acid akanyungudika muropa akanyanya kukosheswa uye mamiriro emuno akanaka (kunyanya acidity yakakwana yepakati), iwo anodonhedza uye anotungamira kuzvimba kwemuno. Izvi zvinosarudzika zvinokanganisa mubatanidzwa wechigunwe chikuru chetsoka. Chete 1 muvanhu gumi vane uric acid yakawandisa muropa ravo ndivo vanozowana gout, saka iwe unoda kuwedzera kubata kuti utore.

• Urinary lithiasis.

Izvo zvinokonzerwa nekuvapo kweimwe kana mamwe matombo mune weti turakiti uye vane basa renal colic. Urolithiasis chirwere chakajairika kubvira 1 kusvika 2% yehuwandu inobatwa muFrance.

Kuongororwa kweiyo mwero weasidhi imwe inogona kuitiswa muropa uye / kana mumurini:

• kuongororwa kweropa kunosanganisira muyenzaniso weropa rinotapuka, kazhinji mukatikati megokora;
• uric acid mumuti weti inoyerwa pamusoro pemaawa makumi maviri nemana: kuti uite izvi, zvinokwana kuita weti mumudziyo wakapihwa izvi uye unopihwa nevashandi vekurapa kwezuva rimwe nehusiku humwe.

Ziva kuti zvinokurudzirwa kusadya kana kunwa chero chinhu mukati maawa anotangira bvunzo.

Pane zvinhu zvakawanda zvinogona kukanganisa uric acid muropa kana weti. Izvi zvinosanganisira:

• chikafu (chakaipa kana chakakwira purine);
• zvinodhaka (kusaina gout, aspirin, kana kunyange diuretics);
• zera, vana vane tsika dzakaderera;
• jenda, nevakadzi kazhinji vane mwero wakaderera pane varume;
• uremu, vanhu vakafutisa vane mwero wakakwirira.

Mishonga yekurapa kana iyo hyperuremia iri chiratidzo zvinotevera: 

• Nucleic acid synthesis inoderedza, senge allopurinol. Iwe unofanirwa kuve wakangwarira nekuti kune kwakawanda kudyidzana nemimwe mishonga.
• Mishonga inodzivisa renal uric acid kudzoreredza, senge benzbromarone.
• Enzymatic kurapwa iyo inowanzo kukonzera matambudziko ehurwere.

Chero chii chinoitika, ndiye chiremba anofanirwa kusarudza kuti kurapwa kunofanira kuteverwa here, uye ndeupi wakanyanya kukodzera.