Alzheimer. Hunhu huviri hunoita kuti munhu aite dementia. Ndeipi njodzi yako?

Alzheimer's isingachinjiki inoparadza uropi, ichibvisa ndangariro uye kugona kurarama wakazvimirira. Pasinei nokuti makumi emamiriyoni evanhu ari kutotambura nazvo (uye nhamba iri kukura nokukurumidza), chirwere ichi chichiri kuvanza zvakavanzika. Izvo hazvisati zvazivikanwa chaizvo izvo zvinokonzeresa nzira inoparadza mutsinga. Masayendisiti, zvisinei, akawana nzira yakasiyana. Zvinoitika kuti hunhu huviri hunogona kufarira kukura kweAlzheimer's. Chii chaizvo chakawanikwa?

1. Alzheimer's chirwere chepfungwa chisingadzoreki chinoparadza zvishoma nezvishoma ndangariro nemano ekufunga. - Zvinosvika pakuti munhu haayeuke zvaakaita kare kana zvakaitika kare. Pane kuvhiringidzika uye kusabatsira - anodaro chiremba wetsinga Dr. Milczarek
2. Kuunganidzwa kweamyloid plaques uye tau muuropi kunozivikanwa kuve kwakabatana nechirwere cheAlzheimer uye hukama hwakafanana.
3. Tsvagiridzo yakaitwa nemasaenzi yakaratidza kuti hunhu huviri hunogona kuve hwakabatana nekukura kweAlzheimer's, uye kunyanya nekuiswa kwezvinhu izvi muuropi.
4. Rumwe ruzivo rwakakosha runogona kuwanikwa pane iyo Onet peji rekutanga.

Chirwere cheAlzheimer - Chii Chinoitika Kwauri uye Nei

Chirwere cheAlzheimer chirwere chisingarapike cheuropi chinoparadza neurons (uropi hunoderera zvishoma nezvishoma), uye saizvozvowo chiyeuchidzo, kukwanisa kufunga uye, pakupedzisira, kukwanisa kuita mabasa akareruka. Chirwere cheAlzheimer chiri kufambira mberi, zvinoreva kuti zviratidzo zvinokura zvishoma nezvishoma mumakore akawanda, zvichiita kuti pave nematambudziko akawanda.

Muchikamu chepamusoro, murwere haachakwanisi kuita mabasa ezuva nezuva - haakwanisi kupfeka, kudya, kuzvigeza, anova anonyatsoenderana nekutarisirwa kwevamwe. - Zvinosvika pakuti munhu haayeuke zvaakaita kare kana zvakaitika kare. Pane kuvhiringidzika uye kusabatsira - akadaro chiremba wetsinga Dr. Olga Milczarek kubva kuSCM Clinic muKrakow mubvunzurudzo yeMedTvoiLokona. (Bvunzurudzo Yakazara: MuAlzheimer's, uropi hunoderera uye hudiki. Sei? Anotsanangura kudaro chiremba wetsinga).

Zvinonyatsozivikanwa kuti chikonzero chechirwere cheAlzheimer ndechekuvakwa kwemhando mbiri dzeprotein muuropi: iyo inonzi beta-amyloid; uye mapuroteni etau kutora nzvimbo yemasero etsinga. - Iyi nzvimbo inova granular, yemvura, spongy, inoshanda zvishoma uye zvishoma uye pakupedzisira inonyangarika - anotsanangura Dr. Milczarek. Nzvimbo inounganirwa nemishonga iyi inotarisa zviratidzo zvichaonekwa mumurwere akapihwa.

Zvinosuruvarisa, hazvisati zvanyatsozivikanwa kuti chii chinoparira iyi nzira inoparadza. Zvinogona kunge zvichipesvedzerwa nekubatanidzwa kwemajini, zvakatipoteredza uye mararamiro ehupenyu. Kukosha kwechimwe cheizvi mukuwedzera kana kuderedza njodzi yekubatwa nechirwere ichi kunogona kusiyana pamunhu nemunhu. Mundima iyi, masayendisiti akawana chiwanwa chinofadza zvikuru. Zvinoitika kuti maviri z hunhu hunhu hunogona kufarirwa kana kuderedza njodzi yekuparadza shanduko muuropi. Mhedzisiro yeongororo dzakaburitswa mupepanhau resainzi Biological Psychiatry.

Hunhu hunhu hunoumba Big Five. Vanorevei?

Tisati tatsanangura kuti maficha ndeapi, tinofanira kutaura anonzi The Big Five, chimiro chehunhu chine zvinhu zvishanu zvikuru. Vesainzi vakataura nezvavo.

1. Verenga zvakare: Shuga uye cholesterol mazinga uye njodzi yeAlzheimer's. “Vanhu havazivi”

Hunhu uhu hunozivikanwa kuti huchikura hudiki uye, sekureva kwenyanzvi dzehutano hwepfungwa, "hune pesvedzero yakakura pane zvakakosha zvehupenyu". The Big Five inosanganisira:

Amicability - mafungiro kune nyika yevanhu. Hunhu uhwu hunotsanangura munhu akanaka kune vamwe, anoremekedza, anonzwira tsitsi, anovimba, anotendeseka, anoshandira pamwe, achiedza kudzivirira kusawirirana.

Kuvhurika - inotsanangura munhu anoda kuziva nezvenyika, akavhurika kune zvitsva zviitiko / manzwiro anoyerera kubva kune ese ekunze uye emukati nyika.

Extroversion - anonyora murume ari kutsvaga kufara, anoshanda, anoshamwaridzana, anoda kutamba

Kungwara - inotsanangura munhu ane mutoro, anosungirwa, akangwara, ane chinangwa uye ane ruzivo, asi zvakare akangwarira. Kunyange zvazvo kunyanyisa kwounhu uhwu kungatotungamirira kukuva nebasa, munhu asina simba anoreva kusava nehanya zvikuru nokuita mabasa ako uye kuva anongoerekana aita chiito.

Neuroticism - zvinoreva katsika kekunzwa manzwiro asina kunaka, akadai sekufunganya, hasha, kusuwa. Vanhu vane mwero wepamusoro weiyi hunhu vanowanzo shushikana, vanosangana nematambudziko ese zvakanyanya, uye akajairwa mamiriro ehupenyu anogona kuita seanotyisidzira uye achishungurudza kwavari. Vane nguva yakaoma yekudzokera mukuenzana kwepfungwa, uye kazhinji zvinotora nguva yakareba.

Vatsvakurudzi vakaita ongororo mbiri dzakatungamirira kune imwe mhedziso. Inoreva maitiro maviri ekupedzisira eBig Five: kungwarira uye neuroticism.

Maitiro maviri eBig Five uye maitiro avo pakuvandudza kweAlzheimer's. Zvidzidzo zviviri, mhedziso imwe

Vanopfuura vanhu vatatu vakapinda mutsvakurudzo. vanhu. Chekutanga, takaongorora data kubva kuvanhu vari kutora chikamu muBaltimore Longitudinal Chidzidzo cheKuchembera (BLSA) - Chidzidzo cheAmerica chakareba kwazvo pamusoro pekuchembera kwevanhu.

Kuti vaone zvimiro zveBig Five, vatori vechikamu vakapedza gwaro remibvunzo rine 240 zvinhu. Mukati megore rimwe rekupedzisa gwaro iri, vatori vechikamu vakatariswa kuvepo (kana kusavapo) kweamyloid plaques uye tau muhuropi hwavo. Izvi zvakaitwa kuti zvigoneke nePET (positron emission tomography) - bvunzo yekufungidzira isiri-invasive.

Basa rechipiri raive meta-analysis yezvidzidzo gumi nembiri zvakatsvaga hukama pakati peAlzheimer's disease pathology uye hunhu hunhu.

I BLSA-based study uye meta-analysis yakatungamirira kumhedziso imwechete: kushamwaridzana kwakasimba pakati pengozi yekukura kwedementia kwakabatana nemaitiro maviri: neuroticism nehana. Vanhu vane mwero wepamusoro weuroticism kana kuderera kwehana vaive mukana wekugadzira amyloid plaques uye tau tangles. Vanhu vane zvibodzwa zvepamusoro zvehana kana zvibodzwa zvakaderera zveurouroticism vanga vasina mukana wekuzviwana.

1. Tsvaga zvimwe: Vechidiki vanobatwawo nedementia uye chirwere cheAlzheimer. Kuziva sei? Zviratidzo zvisina kujairika

Mumwe anogona kubvunza kana hukama uhu hunotanga nehumwe nhanho yekusimba kwezvose zviri zviviri. Dr. Antonio Terracciano, weFlorida State University Dhipatimendi reGeriatrics, ane mhinduro: Aya marongero anoita seane mutsara, asina chikumbaridzo […], uye pasina mwero chaiwo unokonzera kuramba kana kukurumidza.

Chidzidzo chambotaurwa chaive chechimiro chekutarisa, saka haina kupa mhinduro kumubvunzo wekuti ndedzipi nzira dziri shure kwechiitiko chakawanikwa. Nepo kumwe kutsvagisa kuri kudiwa pano, masayendisiti ane akati wandei dzidziso.

Maererano naDr. Claire Sexton, mutungamiriri wezvirongwa zvekutsvakurudza uye rubatsiro kuAlzheimer's Association (isina kubatanidzwa mukutsvakurudza), "imwe nzira inogona kuitika ndeyekuzvimba kunokonzerwa neunhu uye kukura kweAlzheimer's biomarkers." "Mararamiro ndeimwe nzira inogona," Dr. Sexton anoti. - Semuyenzaniso, vanhu vane kungwarira kwepamusoro vakaratidzirwa kutungamirira mararamiro ane hutano (maererano nekuita basa remuviri, kusvuta, kurara, kukurudzirwa kwepfungwa, nezvimwewo) kupfuura avo vane hana shoma.

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