Le Fer chinhu chakakosha chinoumbahemoglobin, mapuroteni aripo Masero matsvuku uye iro basa guru nderekutakuraOksijeni musangano.

Izvo zvakakoshawo kune mamwe mabasa emuviri, senge DNA synthesis kana mamwe maitiro enzymatic.

Inenge 70% yesimbi yemuviri inosungwahemoglobin, apo zvimwe zvacho zvakasimbiswa kutakura mapuroteni (The ferritin or transferrin) kana kuchengetwa mune mamwe matishu emuviri. Somuenzaniso, mumwongo, iron inochengetwa uye inoshandiswa sezvinodiwa kugadzira masero matsvuku eropa matsva.

Simbi inobvachikafu (chiropa uye dzimwe nyama, mazai, hove, kana kunyange miriwo yakasvibirira). Inonyanya kukosha panguva yekukura, pamuviri, kuyamwisa kana mushure mekubuda ropa kukuru.

Iyo assay inobvumidza iwe kuti uongorore mwero wesimbi mumuviri uye kuti wakaita sei metabolized (kureva kuti akapinzwa nemuviri). Izvi zvinobvumira chiremba kuti aongorore semuenzaniso kushaikwa kwesimbi (iron kushomeka), iron inoshaya anemia (anemia nekuda kwekushaya iron), hemochromatosis (simbi yakawandisa mumuviri), asiwo kutarisa hutano hwemurwere.

Yambiro: kutsunga kweferritin kunowanzoitwa kutanga, chiyero chesimbi chete hachiwanzo kuratidzwa (chinogona kuitwa nechiyero chetransferrin mune yechipiri chinangwa).

Chiyero chegoridhe chekufungidzira huwandu hwesimbi mumuviri ndeichibvunzo dzemwongo, kubva pabhonzo aspiration kana biopsy. Iko invasive uye inoshungurudza kuongorora iyo saka isingaitwe nguva dzose.

Kutemerwa kweserum iron (muropa) kunogona kuitwa neropa re venous samples, kazhinji inotorwa pakapetwa pagokora. Kashoma kuitwa ega nekuti ine zvishoma zvekuongororwa kukosha. Kazhinji kazhinji, inosanganiswa nemamwe maedzo akadai seayo serum transferrin, uye dzimwe nguva iyo serum ferritin, soluble transferrin receptors kana intraerythrocytic ferritin.

Sezvo chiyero chesimbi chakakwira mangwanani, kuongororwa kunofanirwa kuitika panguva ino yezuva.

Iyo iron level muropa inowanzova pakati pe70 ne175 μg / dl (micrograms per deciliter) muvarume uye pakati pe50 ne150 μg / dl muvakadzi, asi inosiyana zvakanyanya mumunhu mumwechete mukati mezuva (amplitude ye30 kusvika 40). %). Ichi ndicho chikonzero nei zvakakosha kubatanidza dosage ye transferrin uye kuverenga iyo transferrin saturation coefficient.

Yakakwira serum iron mazinga anogona kuve chiratidzo che, pakati pezvimwe zvinhu:

• a hemochromatosis  (simbi yakawandisa)
• hemolytic anemia (kuparadzwa kusati kwasvika kwemasero matsvuku eropa muropa)
• hepatic necrosis
• hepatitis (kuzvimba kwechiropa)
• cirrhosis
• chidhakwa chisingaperi
• kuwedzerwa ropa kakawanda

Pane zvinopesana, yakaderera mwero wesimbi inogona kubatanidzwa ne:

• kurasikirwa kukuru kweropa, kunyanya panguva dzinorema
• pamuviri
• kushaya simbi (iron deficiency) yakabatanidzwa nechikafu
• kushomeka kunoenderana nekusakwanisa kutora iron zvakanaka
• kubuda ropa mudumbu (maronda, kenza yekoloni, hemorrhoids)

asiwo kuzvimba, hutachiona, mushure mekuvhiyiwa, nezvimwe.

Zvekare, zvinofanirwa kucherechedzwa kuti dhizaini iyi, inoitwa yakazvimiririra, haina chido chekurapa.