Kukadzi 24, 2012 - Kunyange ichinyanyo shandiswa, nonsteroidal anti-inflammatory drug (NSAIDs) inoita kunge inopa njodzi chaiyo kuhutano. Pakati pezvinonyanya kuzivikanwa pane aspirin, Advil®, Antadys®, Ibuprofen® kana kunyange Voltarene®, mishonga inowanzo gadzwa.

Iyi kirasi yemishonga inorwisa-kupisa inofungidzirwa kuti inogona kukuvadza moyo neitsvo. Chokwadi, NSAID dzakabatwa nemhosva ye:

• Matambudziko emwoyo

Kunyaradza marwadzo, asiri-steroidal anti-anogumbura madhiragi anodzivisa kuita kwema enzymes maviri (= protein kubvumidza biochemical chiito) inonzi COX-1 uye COX-2.

Kuvharira COX-2 nemaNSAID kunodzivirira kugwamba kweropa uye kusangana kwetromboxanes, mahormone ane basa revasoconstrictor, zvichidaro kuwedzera kuwedzerwa kweropa uye njodzi dzemwoyo.

• Maronda uye kubuda ropa mudumbu

COX-1 inobvumira kuumbwa kweprostaglandin, metabolites inogadzirwa mudhara, itsvo nemoyo. Kuvhiringidzwa kwe COX-1 nema nonsteroidal anti-anogumbura zvinodhaka anobva azvidzivirira kubva kudzivirira nzira yekugaya, uye zvichizogona kukonzera peptic ulcer.

• Renal kutadza

Uku kuvharirwa kweCOX-1 kwaizosimudzirawo kukundikana kweitsvo nekudzora kuzorwa kweitsvo.

Muzhinji, ndivo vakweguru vanonyanya kunetsekana nenjodzi idzi, nekuti yavo renal basa inoderera, chinokatyamadza, apo isu tichiziva kuti mishonga inorwisa-kuzvimba yakatemwa zvakanyanya kurerutsa marwadzo ane hukama neosteoarthritis.

Anaïs Lhôte - PasseportSanté.net

Source: Mishonga yako, Philippe moser