Craniopharyngioma ibundu risingawanzoitiki reuropi. Sezvo inokura, inoguma ichikonzera misoro, kuvhiringidzika kwekuona uye dzimwe nguva kukanganiswa kwehomoni kwakakosha. Chirwere chakakomba chaimbouraya muvana nevakuru, chine fungidziro iri nani nhasi nekuda kwekufambira mberi mukuvhiya. Zvakadaro, kuvhiya kunoramba kuchirema uye kwakatetepa ... Kurapwa kweHormonal kungave kuri madikanwa kwehupenyu.

tsananguro

Craniopharyngioma ibhenign - kureva kuti, isiri kenza - inononoka kukura bundu rinokura munzvimbo yakati yehuropi pedyo nepituitary gland.

Kunyarara kwenguva refu, inoguma ichimanikidza uropi matishu painokura, zvichikonzera zviratidzo zve intracranial hypertension (musoro, kusagadzikana kweziso).

Zvichienderana nehukuru hwayo, inogona kukonzera kumwe kukuvadza:

• Maonero asina kunaka anoratidza kukuvara kwetsinga dzemaziso.
• Endocrine kusagadzikana kwakabatana nekukuvadza kune pituitary gland, conductor yehomoni system.
• Neurological disorder inogonawo kuitika.

Zvinokonzera

Kuwanda kusingadzoreki kwemaembryonic cells atovepo mufetus ndiko kunokonzera kuumbwa kwebundu. Hatizivi chikonzero, asi tinoziva kuti nhaka haina kubatanidzwa.

chirwere

Kuvepo kwecraniopharyngioma kunofungidzirwa kana kuratidzwa kwayo kukanyanya kukosha kuti irege kufuratirwa.

• Kuongororwa kunonyanya kuenderana nekufungidzira kwehuropi. MRI uye CT scans inogona kuona nzvimbo chaiyo yebundu uye, sekutonga, inosiyanisa kubva kune mamwe marudzi emamota europi.
• Iko kuongororwa kwemahomoni kunoita kuti zvikwanise kukwidziridza nekureruka dosi muropa kushomeka mukukura kwehomoni, mahormone ebonde kana thyroid mahormone.
• Iyo fluid restriction test inoshandiswa kuongorora chirwere cheshuga insipidus. Inoita kuti zvikwanise kuongorora mhedzisiro yemurwere yekusavapo zvachose kwekunwa kwemaawa mashanu kusvika gumi nemashanu. Inoitwa munzvimbo yechipatara.
• Kuongororwa kwe fundus kunoratidza kukuvadzwa kwetsinga yemaziso.

Vanhu vane hanya

Craniopharyngioma inowanzowanikwa muvana vane makore ari pakati pe5 ne15. Asi dzimwe nguva inokura gare gare, neimwe nhamba yepamusoro inoitika pakati pemakore 60 ne75.

Mumwe muvanhu makumi mashanu angave kunetseka. Craniopharyngioma inomiririra isingasviki 5% yemamota muvana vari pasi pemakore gumi nemana.

Intracranial hypertension inoratidzwa nekurwadziwa kwemusoro, kunowedzera nekukosora kana kushanda nesimba. Inokonzerawo kurutsa kwejeti, pasina kudya kwekudya.

Hormonal disorders yakabatana nekukuvadzwa kwepituitary gland, iyo inogadzira kukura kwehomoni uye akasiyana mahormone anodzora secretions kubva kune mamwe endocrine glands mumuviri, uye anoburitsa antidiuretic hormone inogadzirwa mu hypothalamus (iri pamusoro apa).

• Kuderera kwekukura kunokonzerwa nekushaikwa kwekugadzirwa kwekukura kwehomoni. Chiratidzo chinowanzoitika, chiripo mumumwe muvana vatatu.
• Kuyaruka kunononokawo mune inodarika hafu yenyaya.
• Mu20% yezviitiko, kushaikwa kwekugadzirwa kweantidiuretic hormone kunotungamirira kuchirwere cheshuga insipidus, chinoguma nekubuda kweweti yakawandisa, kugara uchimuka husiku kuita weti kana weti pamubhedha. Mwana (kana kuti munhu mukuru) ane nyota nguva dzose, anonwa zvakawanda, kana zvisina kudaro anokurumidza kupera mvura mumuviri.
• Kufutisa, kunowanikwa mu10 kusvika ku25% yevana panguva yekuongororwa, kwakabatana nekusaenzana kwehomoni uye / kana nzara isingadzoreki inokonzerwa nekudzvanywa kwenzvimbo yekudya mu hypothalamus.

Kukanganiswa kwekuona kunogona kuve kukuru. Kukuvadza kune optic nerve kunokonzera kuderera kwechiratidzo mune rimwe kana maziso ose (amblyopia) kana kuderedzwa mumunda wekuona nekuda kwayo.

Neurological disorders dzimwe nguva inooneka:

• ndangariro, kudzidza uye kutarisisa matambudziko,
• pfari, kuoma mitezo kune rimwe divi remuviri kana kumeso,
• kukanganisa mukugadzirisa kupisa kwemuviri,
• matambudziko ekurara.

Kuvhiya kurapa

Kufambira mberi kwemaitiro ekuvhiya kwakapa tariro itsva kumhuri dzakabatwa nechirwere ichi chaimbouraya, kunyangwe kukuvara kwekuona kana tsinga kukaramba kusingagadzirisiki. Kupindira kune chinangwa chekubvisa bundu (excision) nekukurumidza uye zvakakwana sezvinobvira.

Diki craniopharyngiomas inogona kubviswa nemhino, asi kazhinji inofanirwa kuvhura dehenya. Kupindira kunoramba kwakaoma, nengozi yekufa pakati pe1 ne10%.

Craniopharyngioma inogona kubviswa yakazara kaviri kubva katatu. Mune zvimwe zviitiko, zvisaririra zvemicroscopic zvinoratidza kuti hazvibviri kubvisa uye, kamwe mugumi, chikamu chete chebundu chinobviswa.

Muyero wekudzokorora ndeye 35 kusvika 70% kana kuchekwa kusina kukwana, uye 15% kana bundu rabviswa zvachose. 

Radiotherapy

Inogona kupihwa muchiitiko chekudzokazve kana bundu masara, uye inobvumira 70% yevarwere kuti varapwe zvachose. Pasina kurwadza, nguva dzekuisa irradiation dzinotora maminitsi gumi nemashanu.

Gamma banga (radiochirurgie)

Gamma Knife radiosurgery inoshandisa gamma mwaranzi ine simba kwazvo kuparadza mapundu madiki mumwaranzi mumwe chete. 

Kurapa kweHormonal

Iyo pituitary gland inowanzokuvadzwa zvachose mushure mekuvhiyiwa. Mahomoni ekutsiva anopihwa kutsiva kushomeka kwehomoni, zuva nezuva uye kazhinji kwehupenyu:

• Kukura kwehomoni kunorongerwa vana vakamira kukura, dzimwe nguva zvakare kune vanhu vakuru nekuda kwebasa rayo mumetabolism.
• Mahomoni ebonde anobvumira kuyaruka uye zvinozoita zvakajairika kuita zvepabonde. Majekiseni eGonadotropin anogonawo kupihwa kurapa matambudziko ekuzvara.
• Mahomoni etirodhi anoita basa rakakosha mumetabolism pamwe nekuvandudza skeleton uye nervous system.
• Desmopressin inobata chirwere cheshuga insipidus.
• Glucocorticoids yakakosha pakugadzirisa kushushikana uye metabolism.

Kutsigira kwevarwere

Dzidzo yekurapa

Izvo zvinodikanwa kubata nemazvo kurapa kwehomoni.

Kutsigirwa kwepfungwa

Inobatsira kutsungirira chiziviso chekuongororwa, kushanda, njodzi yekudzoka zvakare kana zvipingamupinyi zvekurapa kwehomoni.

Kusadzoreka kwekudya (kuwandisa) kunowanzoitika mhedzisiro yekuvhiyiwa, kwakabatana nekukuvadza kune hypothalamus. Kudya kusinga peri kana kumanikidzwa kwechikafu kunoratidza kunge kusingaite kudzora, zvichitungamira kune uremu dzimwe nguva zvakakosha uye kumatambudziko epfungwa. Kuonana nenyanzvi munyaya dzekudya kunogona kubatsira.

Kuchengetedzwa kwakakosha

Mushure mekuvhiyiwa, humwe hurema hunoda kuteedzerwa kwakasarudzika.

• Kusvika 30% yevarwere vane hurema hwekuona.
• Zvinetso zvendangariro zvinowanzoitikawo.