Kuongororwa kweacromegaly kuri nyore (asi chete kana iwe uchifunga nezvazvo), sezvo zvinosanganisira kutora kuongororwa ropa kuti uone chiyero cheGH uye IGF-1. Mu acromegaly, pane yakakwirira ye IGF-1 uye GH, kuziva kuti kuvharidzirwa kweGH kunowanzopindirana, asi kuti mu acromegaly inogara yakakwirira nokuti haichagadziriswi. Iyo yechokwadi murabhoritari kuongororwa kunobva pane iyo glucose bvunzo. Sezvo glucose kazhinji inoderedza kuvharwa kweGH, kutungamira kwemuromo kweglucose kunoita kuti zvikwanise kuona, nekutevera kuongororwa kweropa, kuti, muacromegaly, secretion yekukura kwehomoni inoramba yakakwirira.

Kamwe iyo hypersecretion yeGH yakasimbiswa, zvinozodiwa kuti uwane kwayakabva. Nhasi, chiyero chegoridhe iMRI yehuropi inogona kuratidza bundu repituitary gland. Muzviitiko zvisingawanzoitiki, ibundu rinowanikwa kune imwe nzvimbo (kazhinji muuropi, mapapu kana pancreas) inobudisa imwe hormone inoshanda papituitary gland, GHRH, iyo inokurudzira kugadzirwa kweGH. Ongororo yakawedzera inozoitwa kutsvaga kwakabva kuvharika uku.