Zviratidzo zvecholestasis
Zviratidzo zvekiriniki zvecholestasis zvinotongwa nea jaundice (yellow color yeganda uye integuments) yakabatana ne rima urinhi, discolored stool uye mumwe pruritus (itching).
Muchiitiko che extrahepatic cholestasis, hepatomegaly (kuwedzera kwehuwandu hwechiropa hunoonekwa pakuputika kwedumbu), gallbladder yakakura uye fever inogona kuonekwa nachiremba panguva yekuongorora kwepanyama.
Zvichienderana nechikonzero checholestasis, zvimwe zviratidzo zvekiriniki zvisiri izvo zvinogona kuwanikwa (semuenzaniso kurasikirwa nehuremu mugomarara).
Kuongororwa kweropa kunoratidza:
-a kuwedzera alkaline phosphatase icho chinhu chakakosha mukuongororwa kwecholestasis.
-kuwedzera kwegamma-glutamyl transpeptidase (gGT). Kuwedzera uku hakusi kwakananga kwecholestasis uye kunogona kucherechedzwa mune zvese chiropa uye biliary kusagadzikana (kudhakwa semuenzaniso)
- kuwedzera kwe conjugated bilirubin, inokonzera jaundice
-zviratidzo zvevhitamini A, D, E, K kushomeka
-kuderera kweprothrombin (PT) level yakabatanidzwa nekuderera kwechinhu V (coagulation protein) muhepatocellular insufficiency
Kuti uwane chikonzero che cholestasis, tsvagaAbdominal ultrasound ndiyo ongororo yekutanga, inoratidza kuwedzera kwebile ducts mune zviitiko zve extrahepatic cholestasis. Muchiitiko che intrahepatic cholestasis, abdominal ultrasound haiwani kuwedzera kwe bile ducts.
Sechinangwa chechipiri, chiremba angangofanira kupa mamwe maedzo eradiological:
- cholangiopancreatography (x-ray ye bile ducts mushure mekushandisa chigadzirwa chakasiyana)
- un scanner mudumbu
-An MRI (Nuclear Magnetic Resonance Imaging) ye bile ducts
- endoscopy
Mukushaikwa kwekusagadzikana kwe bile ducts inoratidzwa neiyo ultrasound, dzimwe ongororo dzinoitwa kuratidza chikonzero checholestasis:
-specialized blood tests (kutsvaga ma-anti-mitochondrial antibodies uye antinuclear antibodies) inogona kunge inoratidza yekutanga biliary cirrhosis.
- kutsvaga mavhairasi anokonzera hepatitis anogona kuitwa
Kana idzi bvunzo dzakasiyana-siyana dzisina kuratidza chikonzero chaicho, biopsy yechiropa inogona kudikanwa.
Nyaya inokosha: cholestasis yepamuviri. -Inowanzoitika kakawanda mukati mechikamu chechitatu chekuzvitakura uye ndeye ngozi kune fetus. -Iyo nzira yakabatanidzwa nekuunganidza bile acids muropa reamai; Aya akawandisa bile acids anogona kuyambuka placenta uye kuungana muropa re "fetus". -Isingasviki 1% yemimba inobatwa necholestasis yekuzvitakura [1] -Njodzi ye cholestasis yekuzvitakura inowedzerwa muchiitiko chekubata mapatya, nhoroondo yemunhu kana yemhuri ye cholestasis yekuzvitakura. -Inozviratidza ne pruritus (kukwenya kwakanyanya) zvakanyanya muzvanza zvemaoko uye pasi petsoka, asi muviri wese unogona kunetseka. Kana pasina kurapwa, jaundice inogona kuonekwa -Kuongororwa kunosimbiswa nekuongororwa kweropa rehupenyu kunoratidza kuwedzera kwebile acids -Njodzi, diki kuna amai, inogona kunge yakakomba kune fetus: kutambura kwe fetal uye njodzi yekusununguka nguva isati yakwana -Kurapa neursodeoxycholic acid kunoderedza kuwedzera kwebile acids uye pruritus -Mushure mekusununguka, pruritus inopera zvishoma nezvishoma uye kushanda kwechiropa kunodzokera kune zvakajairika -Kutarisisa kunofanirwa panguva yekuzvitakura kunotevera. |