Chirwere chePaget chinogona kukanganisa pfupa rimwe kana akawanda. Zvinongobata chete mapfupa akatanga kukanganiswa (hapana kuwedzera kunogoneka pane mamwe mapfupa).

Iyo inowanzo asymptomatic, yakawanikwa nemukana panguva yekuongororwa kweradiographic kune chimwe chikonzero.

Zvizhinji zviratidzo zvekiriniki zvinogona kuratidza chirwere uye kururamisa kunyorerwa kweradiological bvunzo:

-kurwadziwa kwepfupa

-kushomeka kwemapfupa : haachinji uye anonoka (chiratidzo cheheti ne hypertrophy [kuwedzera muvhoriyamu] yedehenya, saber-blade tibia, flattening of the thorax, deformation of the spine [kyphosis])

-zvinonetsa vasomoteurs (blood vessel abnormalities) inokonzera hyperemia (kuwanda kweropa kunokonzera kutsvuka) kweganda riri pedyo nemaronda emapfupa.

Cherechedza kuti hapana kuparara mumamiriro ezvinhu.

Mapfupa anonyanya kubatwa nechirwere ichi ndiwo mapfupa echiuno, dorsal uye lumbar vertebrae, sacrum, femur, dehenya, tibia.

The x-rays zvinoita kuti zvikwanise kuratidza zviratidzo zvechirwere:

- kusaenzana kwechimiro: bone hypertrophy (kuwedzera kwehuwandu)

-kukanganisa kwemaitiro: kukora kwecorticals (mapfupa emadziro)

-density anomalies: heterogeneous condensation yebhonzo inopa kutaridzika kwepadded

Bone scintigraphy inogona kusimbisa yakanyanya hyperfixation pamapfupa akakanganisika. Chinonyanya kufarira chekuongorora uku ndechekuona mapfupa anokonzerwa nechirwere. Nekudaro, hapana chikonzero chekuchidzokorora panguva yekutarisa uye kurapwa kwemurwere.

Kuwedzera kwealkaline phosphates muropa kunoenderana nehuwandu uye basa rechirwere. Inoratidza kushanda kwakanyanya kwekuumbwa kwemapfupa. Muyero uyu unogona kunge wakajairwa kana chirwere chikaiswa pabhonzo rimwe chete.

Iyo dosages ye crosslaps (inonziwo CTx kana NTx) uye pyridinolines muropa kana weti inowedzerwa uye inopupurira basa rekuparadza mapfupa.

Kusiyana nekuongorora kwebhonzo, ma scans aya anobatsira pakuongorora chirwere chiri pasi pekurapwa. Sezvo zvakadaro, dzinoitwa mwedzi mitatu kusvika ku3 yega yega.

Kuziva kuti:

-calcemia (calcium level muropa) inowanzojairika. Inogona kuwedzerwa muchiitiko chekugara kwenguva refu kana kusanganisa hyperparathyroidism.

-iyo sedimentation rate zvakare yakajairika.

The zvinetso Chirwere chacho chinosiyana-siyana kubva kune mumwe murwere kuenda kune mumwe uye ndechekurongeka kunotevera:

-kutaura : kunyanya kunobata hudyu nemabvi, ivo vanobatanidzwa nekuremara kwemagumo emapfupa anokonzerwa nechirwere uye vane mhosva yekurwadziwa, kushanduka uye kusaita basa.

-bone : kuputsika kunokonzerwa nemapfupa asina simba

Kakawanda, matambudziko anogona kumuka:

-nerve : ine chekuita nekutsikirirwa kwetsinga nekuchinja kwemapfupa. Saka, zvinokwanisika kuona matsi kazhinji kazhinji bilateral (inobata nzeve mbiri), paraplegia (iyo inogona kurapwa)

-mwoyo : moyo kupera

Kunyanya, kuitika kwechirwere chakaipa kunogona kuitika papfupa rinobatwa nechirwere (humerus uye femur). Kuwedzera kwemarwadzo uye zvisizvo zveradiographic zvinogona kuratidza chirwere ichi, chinogona kungosimbiswa nechokwadi nekuita biopsy.

Chirwere chePaget hachifanire kuvhiringidzwa ne:

- hyperparathyroidism

-bone metastases kubva kugomarara rezamu kana kenza yeprostate

- multiple myeloma (inonziwo chirwere chaKahler)