Trisomy 18 inozivikanwa nekuvapo kwechimwe chromosome 18, mukati memamwe masero emuviri kana mune rimwe nerimwe remasero aya. Mhando mbiri dzechirwere dzinozivikanwa uye kuomarara kweDown's syndrome kunoenderana nazvo.

Trisomy 18, inonziwo "Edwards Syndrome" chirwere chinokonzerwa nekromosomal zvisizvo. Inotsanangurwa nekusagadzikana munzvimbo dzakasiyana dzemuviri.

Varwere vane Trisomy 18 vanowanzo kuve nekukanganisa kwekukura vasati vaberekwa (intrauterine kukura kunonoka). pamwe nehuremu husina kujairika. Zvimwe zviratidzo zvinogona zvakare kuve zvine hukama nechirwere ichi: kushaya moyo, kushomeka kwemamwe mitezo, nezvimwe.

Trisomy 18 inosanganisirawo mamwe maitiro: chimiro chisina kujairika chedehenya remwana, shaya diki uye muromo wakamanikana, kana kutosunga-mukati mawoko neminwe inopindana.

Uku kurwisa kwakasiyana kunogona kuve kwakakosha kumwana. Muzviitiko zvakawanda, mwana ane trisomy 18 anofa asati aberekwa kana mwedzi wake wekutanga usati wasvika.

Ivo vanhu vanopona mushure memwedzi wekutanga kazhinji vane hurema hwakakura hwekuziva.

Ngozi ye Down's syndrome inosanganisirwa nepamuviri mumukadzi chero zera. Uye zvakare, iyi njodzi inowedzerwa mumamiriro ekuzvitakura nepamuviri.

Maitiro maviri chaiwo echirwere akatsanangurwa:

• la fomu yakazara : iyo ine chekuita neinenge 94% yevana vane Down's syndrome. Iyi fomu inoratidzirwa nekuvapo kwekatatu kopi (panzvimbo yemaviri) yekromosome 18, mune yega yega maseru emuviri. Vazhinji vacheche vane fomu iyi vanofa mimba isati yapera.
• la waMosesi chimiro, iyo inokanganisa vangangoita 5% yevana vane trisomy 18. Muchirevo chechinyorwa ichi, kopi katatu yechromosome 18 inongoonekwa zvishoma mukati memuviri (mune mamwe maseru chete). Iyi fomu haina kusimba pane iyo yakazara fomu.

Kukura kwechirwere nekudaro kunoenderana nerudzi rwe trisomy 18 pamwe nenhamba yemasero ane kopi yechromosome 18, in it.

Mazhinji emakesi eTrisomy 18 anokonzerwa nekuvapo kwekatatu kopi yechromosome 18, mukati meimwe sero remuviri (pachinzvimbo chemakopi maviri).

Chete 5% yevanhu vane Trisomy 18 vane imwe yakawandisa, mune mamwe maseru chete. Ichi chidiki chevarwere chakanyanya kushomeka panjodzi yekufa asati aberekwa, kana pamberi pemwedzi wekutanga wemwana.

Zvakawanda zvisingawanzo, ruoko rurefu rekromosomu 18 runogona kubatanidza (translocate) kune imwe chromosome panguva yekubereka kwesero kana panguva yekukura kwembryoni. Izvi zvinotungamira kuvepo kwemaviri kopi echromosome 18, pamwe nekuvapo kwechimwe chromosome 18, uye nekudaro kune matatu ma chromosomes 3. Varwere vane iyi chaiyo fomu yetrisomy 18 vanoratidza zviratidzo zvishoma.

Ngozi yeTrisomy 18 ine chekuita nepamuviri pese. Zvakare, njodzi iyi inowedzera sezvo zera remukadzi ane nhumbu rinowedzera.

Muzviitiko zvakawanda zveTrisomy 18, kufa kwemwana asati aberekwa, kana mumwedzi wekutanga, kunoenderana nazvo. Kana mwana akararama, sequelae inogona kunge ichionekwa: kukura kunonoka mune mamwe mitezo uye / kana nhengo, hurema hwepfungwa, nezvimwe.

Zviratidzo zvekuchipatara uye zvakajairika zviratidzo zvinogona kufanana naTrisomy 18:

• musoro mudiki pane avhareji
• mapako matama uye muromo wakamanikana
• minwe mirefu inopindirana
• nzeve hombe dzakadzika zvakanyanya
• hurema mumuromo unotsemuka

Zvimwe zvechirwere zvinogona kunge zvichioneka:

• itsvo uye kukuvara kwemoyo
• kuramba kudya, zvichitungamira mukushomeka mukukura kwemwana
• kufema zvinetso
• kuvapo kwehernias mudumbu
• kusagadzikana mune skeletal system uye kunyanya musana
• zvakakosha kudzidza matambudziko.

Iyo njodzi yekukudziridza kweTrisomy 18 ndeye genetics.

Chokwadi, kuvapo kwemakopi matatu echromosome 18, mukati memamwe maseru chete kana kunyangwe mune rimwe sero rehupenyu, zvinogona kutungamira mukukura kwechirwere chakadai.

Hapana kurapwa kweTrisomy 18 ikozvino inozivikanwa. Iwo manejimendi echirwere ichi anoshanda neakawanda multidisciplinary hutano timu.

Marapirwo anogona kunyorwa zvakadaro, uye izvi zviri mumamiriro ekurwiswa nemoyo, hutachiona, kana kunetseka pakudya.

La physiotherapy inogona zvakare kurapwa kweTrisomy 18, kunyanya kana mhasuru nemapfupa masisitimu akanganiswa.