La progesterone ndiwo steroid hormone iyo inoita basa rakakosha kunyanya panguva yekuiswa nekuvandudzwa kwe pamuviri. Izvo, zvisinei, zvakakosha kunyange kunze kwekuzvitakura, kuitira kuchengetedza basa rezvikadzi.

Inonyanya kubudiswa ne ovaries (kunze kwepamuviri) uye placenta (kubva pamwedzi wechipiri, kutora kubva kune yellow body). Panguva yekuzvitakura, inobvumira kutama kwezai rakagadzirwa kusvika kuchibereko, zvino inofambisa kuiswa kwayo, pakati pezvimwe zvinhu.

Chiyero cheprogesterone muropa chinosiyana panguva yekuenda kumwedzi. Iyo yakaderera panguva yefollicular phase, inowedzera zvakanyanya panguva ye luteal phase, inosvika pakakwirira mazuva mashanu kusvika gumi mushure mekuvhiya kweLH (iyo luteinizing hormone, iyo inokonzera ovulation). Mitengo inobva yaderera, kunze kwepamuviri.

Muropa, progesterone inotenderera yakasungwa kune mapuroteni akasiyana-siyana (transcortin, albumin uye orosomucoid).

Chiyero cheprogesterone yeropa (progestéronémie) inogona kuitwa mune akati wandei mamiriro:

• pakati pe20^st uye 23^st zuva rekuenda kumwedzi, kuve nechokwadi chekuti corpus luteum inoburitsa yakajairika huwandu hweprogesterone, inodiwa pakusimwa kwepamuviri (kana paine kupokana panguva yekumisikidzazve)
• mumavhiki ekutanga ekuzvitakura, kuve nechokwadi kuti iri kufambira mberi zvakanaka (chiyero chinofanira kuramba chakadzikama)
• kutarisa kushanda kwe ovulation induction mukubatsirwa nemishonga kubereka
• kuongorora ectopic pregnancy (pamwe chete nehCG bvunzo), iyo progesterone ichibva yadzikira zvisingaite.
• kana iri nyaya yekuzvara kunobatsirwa nemishonga, ye in vitro fertilization uye embryo transfer, kana kuti programme intrauterine inseminations (ndiyo mucherechedzo weovulation)

Kuongororwa ropa kunoitwa pane venous sample, kazhinji pagokora regokora. Hapana kugadzirira kunodiwa, asi zuva rekupedzisira nguva kana kutanga kwepamuviri kunofanira kutsanangurwa.

Semutungamiri, mazinga eropa akajairika e progesterone kunze kwepamuviri pasi pe 1,5 ng / mL panguva ye follicular phase, pakati pe 0,7 ne 4 ng / mL panguva yepamusoro-ovulation uye pakati pe 2 ne 30 ng / mL panguva ye luteal phase (kuratidzwa kwekuvapo kwe corpus luteum).

Vanoderera pa kumiswa kwemwedzi.

Panguva yekuzvitakura, pa5st vhiki yeamenorrhea, inenge 40 ng / mL uye inosvika 200 ng / mL pakupera kwe pamuviri.

Kana mazinga akaderera eprogesterone akaonekwa, kunyanya mumukadzi anoda kuve nepamuviri, kuwedzera kunogona kutariswa muchikamu chechipiri chekutenderera.

Pakupedzisira, cherechedza kuti progestéronémie inogona kuwedzerwa mune akati wandei pathologies, kunyanya mamwe ovarian kana adrenal tumors kana kumwe kuperevedza kwekuzvarwa.

Chiremba chete ndiye achakwanisa kududzira mhedzisiro uye kuita chirwere, dzimwe nguva nerubatsiro rwekuwedzera bvunzo kana ongororo.