Andropause: chii ichocho?
PasseportSanté.net yasarudza kutora zvinyorwa zveandropause, kunyange zvazvo isiri chirwere chinozivikanwa nemishonga. Andropause zvakadaro inoratidza chokwadi chazvino sezvo varume vakawanda vezera repakati vanosarudza kutora testosterone kurapwa. Kurapa uku kwakashandiswa kwemakore mazhinji muvarume vechidiki vane innate hypogonadism, kureva kuti kugadzirwa kwehomoni dzepabonde negonads (testes) kwakaderera zvakanyanya nekuda kwedambudziko remajini. . Zvisinei, ichangobva kupiwa kuvarume vane hutano hwepakati-kati. |
Isu tinotsanangura iyoandropause senge zvese zvepanyama uye zvepfungwa zviratidzo zvinogona kuperekedza low testosterone panguvavarume kuchembera. Zvaizowanzoitika kumativi ose 45 kuna 65.
Andropause, kubva muchiGiriki andros, zvinoreva kuti "murume", uye pausis, "Kurega", inowanzoratidzwa sechirume chinoenderana nekuenda kumwedzi. |
Zviratidzo izvi zvinobva kuderera kwechido chepabonde pakusvika kwa matambudziko erectile kuburikidza nekunzwa kwekushaya simba uye kutyaira. Nguva dzekudikitira zvakanyanya, matambudziko ekushaya hope uye kuwedzera huremu zvinogonawo kuwedzera kune zvinokonzeresa kuderera kwekugadzirwa kwehomoni dzepabonde.
Inofungidzirwa kusashanda nevamwe, sechiratidzo che aging zvakajairika nevamwe, andropause inoramba iri a nyaya ine nharo. Uyezve, mushonga chete uripo, testosterone, hauna kuratidzwa, ingave maererano nekubudirira kana kuchengeteka.
Kuenda kumwedzi kune vamwe, uyeropause kune vamwe? Kuenzanisa pakati pe andropause nekuenda kumwedzi kunoremara. Andropause inongobata vashoma vevarume. Zvakare, hazviratidzi kupera kwekubereka. Uyezve, iyo kuderera kwehomoni muvanhu ndizvo kusarura, budiriro et inconstantkusiyana nevakadzi, vane mahormone anodonha zvakanyanya mukati menguva pfupi. Muvarume, kudonha zvishoma mukugadzirwa kwe testosterone kwaizotanga mumakore makumi matatu kana makumi mana. Kubva pane zvakaonekwa nenyanzvi, kuwanda kwe testosterone muropa kunoderera neinenge 1% pagore. |
Varume vangani vakabatwa?
Sezvoandropause hazvizivikanwi uye hazviwanzo onekwa, isu hatina data chaiyo pamusoro pehuwandu hwevarume vanorwara nazvo.
Zvisinei, maererano nechidzidzo chikuru chakabudiswa muna 2010, European Male Aging Study, chete 2% varume vakura 40 kuna 80 vari kusangana ne andropause: chikamu i3% pakati peavo vane makore makumi matanhatu kusvika makumi matanhatu nepfumbamwe uye 60% pakati peavo vane makore 69 kusvika 5.1. Kuongororwa kwaive kwakavakirwa pakuvapo kwezviratidzo zve andropause uye yakaderera pane yakajairika ropa testosterone level.
Mhedzisiro iyi inoratidza kuti kurapwa kwe testosterone kwakakodzera varume vashoma kwazvo, sekureva kwevanyori vezvidzidzo.12. Kazhinji yenguva, maererano nekucherechedza kwavo, zviratidzo zvinowanzoenderana nekukwegura, kufutisa kana rimwe dambudziko rehutano. Muchokwadi, 20% kusvika 40% yevarume vanokura zviratidzo inogona kufanana neye andropause nezera11.
Chokwadi mubvunzo we testosterone?
La Testosterone inopiwa semushonga paandropause kweanopfuura makore gumi. Chinangwa chekurapa ndechekuvandudza hupenyu hwehupenyu nekuderedza zviratidzo. Makambani emishonga anopikisa kuti testosterone inogonawo kunonoka maitiro e aging : kuderera kuderera kwemasumbu uye njodzi yekuputsika, kuwedzera kwehutano hwepabonde, kusanganisira erections zviri nani, nezvimwewo. Zvisinei, izvi zvinokonzerwa nesayenzi hazvina kuratidzwa.
Heano zvinhu zvikuru zvinogadzira andropause kurapwa chidzidzo chakapfava uye chakaoma:
- Le testosterone levels iyo inoratidza "kushomeka" kwevarume vezera repakati hazvizivikanwe. Mukuwedzera, mwero uyu unosiyana kubva kumunhu kuenda kumunhu. Zviyero zviri kushandiswa iye zvino zvine mwero wakakosha wekusarongeka uye zvinoenderana neavhareji yakatemerwa majaya;
- Hapana zviratidzo zvakananga kune andropause. Mune mamwe mazwi, zviratidzo zvose zvinowanikwa zvinogona kuva mhedzisiro yemamwe matambudziko ehutano, akadai sekuora mwoyo, matambudziko evascular kana kufutisa;
- Kushamwaridzana pakati pepasi testosterone uye zviratidzo zve andropause hazvina simba, maererano nezvidzidzo zvakasiyana-siyana. Varume vane mazinga e testosterone akajairika vanogona kuona zviratidzo zve andropause. Dzimwe nyanzvi dzinofunga kuti zviratidzo zve andropause zvinowanzova mugumisiro wezvakaipa tsika dze upenyu2, 11;
- The zvinobatsira uye ngozi kurapwa ne testosterone haisi kunyatsosimbiswa nemiedzo yekiriniki, nguva pfupi uye kwenguva refu. Dzimwe nyanzvi dzinoti testosterone hormone therapy inongova placebo inodhura12. Kutya kukuru nekurapa uku muvarume vakuru ndeyekuti unowedzera njodzi yekenza yeprostate kana sitiroko. Izvi zvinodaro nekuti testosterone inowedzera hemoglobin mazinga uye inogona kushandura zvishoma iyo lipid profiles muropa, ichiwedzera njodzi yekugwamba kweropa kuumba mutsinga iri muuropi. Dzimwe njodzi dzinotaurwa dzinosanganisira: kukuvara kwechiropa, kukura kwezamu (izvo zvinogona kurwadza), testicular atrophy, kuwedzera kwehasha kana kusagarisana nevamwe uye kuipa kwechirwere chehutano chiripo (kutadza kufema kwehope, mania, kuora mwoyo, nezvimwewo). Kufanana nemahomoni anotemerwa kuvakadzi vepashure memenopausal, zvinogoneka izvozvo mumashure kuti kurapwa uku kwe testosterone kunounza dzimwe njodzi dzehutano. Zvidzidzo zviri kuitika;
- Dzimwe shanduko dzemahomoni dzinogona kutsanangura mhedzisiro ye andropause. DHEA (dehydroepiandrosterone), kukura kwehomoni, melatonin uye, kusvika pamwero muduku, mahomoni ethyroid ane simba rawo.
Testosterone Testosterone ndiyo inonyanya kukosha yehomoni yepabonde muvarume. Inobatanidzwa nehupenyu uye virility. Tine chikwereti kwaari chitarisiko chehunhu hwechirume pakuyaruka. Inobatsirawo kuchengetedza hutano hwemapfupa uye kusimba kwetsandanyama uye inomutsa kugadzirwa kwembeu nemasero matsvuku eropa. Nzira iyo mafuta anowedzera mumuviri inokonzerwawo nehomoni iyi. Vakadzi vanoigadzirawo, asi muhuwandu hushoma. Ma testes anoita testosterone. Huwandu hwe testosterone hunogadzirwa hunoenderana nezviratidzo zvinotumirwa nemagland ari muuropi: hypothalamus uye pituitary. Zvinhu zvakasiyana-siyana zvinokurudzira kana kudzivisa kugadzirwa kwe testosterone. Kuita zvepabonde, somuenzaniso, kunomukurudzira. Kana yangogadzirwa, testosterone inofamba nemuropa uye inosunga kune zvinogamuchirwa mumhando dzakasiyana-siyana, uko inoshandisa migumisiro yayo. |
chirwere
Treatment ofandropause kunge ichangoburwa, maitiro anotungamira kuongororwa haana hwaro hwakasimba hwesainzi.
Chiremba anotanga abvunza nezve zviratidzo zvinonzwika nemurwere wake. Anogona kushandisa mamwe mafomu ekuongorora kuratidza zviri nani kusimba kwezviratidzo, seye AMS test (ye Kuchembera Murume Chibodzwa) kana bvunzo yeADAM (ye Kushaikwa kweAndrogen kweMurume Akwegura) Kuti utarise bvunzo idzi, ona Saiti dzekufarira chikamu.
Uyu mukana wakanaka wekugadzira a kuongorora hutano hwakakwana : kuongororwa ropa (lipid profile, thyroid hormones, specific prostate antigen, nezvimwewo), mufananidzo wehutano hwemwoyo, muchidimbu mararamiro emararamiro. Rondedzero yemishonga uye zvigadzirwa zvehutano hwepanyama zvinopedzwa zvinopedza mufananidzo. Kuongorora uku kuchabatsira kusabvisa zvimwe zvinogona kukonzera zviratidzo zvinonzwa (anemia, kuora mwoyo, hypothyroidism, chronic fatigue syndrome, matambudziko ekutenderera kweropa, migumisiro yemishonga, nezvimwewo).
Kuyera ropa
Heano dzimwe tsananguro pamusoro pebvunzo dzinoshandiswa kuongorora kana pane kushomeka kwe testosterone.
Maererano neInternational Society for the Study of Aging Male (ISSAM), bvunzo dzine chinangwa chekuyera tevere testosterone neropa inofanira kunge iri chikamu chekuongororwa sezvo zviratidzo zvingave zvisina hukama ne andropause3. Asi iyi miedzo inoitwa chete kana zviratidzo zvinopfuura chimwe zvichiratidzwa.
- Zvose mazinga e testosterone. Mhedzisiro yebvunzo iyi inosanganisira ese testosterone akasungwa kune mutakuri (the hormone yebonde inosunga globuline kana SHBG uye, kusvika pamwero muduku, albumin) uye testosterone inotenderera zvakasununguka muropa;
- Mahara e testosterone mazinga. Ichi chiyero chakakosha sezvo chiri chemahara testosterone inoshanda mumuviri. Paavhareji, inenge 2% ye testosterone inotenderera zvakasununguka muropa. Hapana muedzo unoyera zvakananga chiyero che testosterone yakasununguka. Naizvozvo vanachiremba vanofungidzira nekuverenga: vanoyera mwero we hormone yebonde inosunga globuline (SHBG) muropa uye wobva waibvisa kubva pachiyero che testosterone.