Aspergillosis chirwere chinokonzerwa nefungus ye genus Aspergillus. Iyi mhando yehutachiona inowanzoitika mumapapu, uye kunyanya muvanhu vasina kusimba uye / kana immunocompromised. Mishonga yakawanda yeantifungal inogona kutariswa zvichienderana nenyaya yacho.

Tsanangudzo yeaspergillosis

Aspergillosis ishoko rezvokurapa rinounganidza pamwe chete zvirwere zvinokonzerwa nefungi ye genus Aspergillus. Izvo zvinokonzerwa nekufema kwezvipembenene zvefungi idzi (izvo zviri mune imwe nzira mbeu dzefungi). Ndicho chikonzero nei aspergillosis inowanzoitika mumhepo yekufema, uye kunyanya mumapapu.

Chikonzero che aspergillosis

Aspergillosis chirwere chine fungus che genus Aspergillus. Mu80% yezviitiko, zvinokonzerwa nemhando Aspergillus fumigatus. Mamwe matambudziko, kusanganisira a. Naija, A. nidulans, A. flavus, uye A. versicolor, inogonawo kuva chikonzero che aspergillosis.

Types d'aspergilloses

Tinogona kusiyanisa marudzi akasiyana easpergillosis:

• Allergic bronchopulmonary aspergillosis iyo inonzi hypersensitivity reaction kune Aspergillus marudzi, inonyanya kuitika muasthmatics uye vanhu vane cystic fibrosis;
• aspergilloma, pulmonary aspergillosis iyo inokonzera kuumbwa kwebhora refungal mumapapu emapapu uye rinotevera chirwere chekare chakadai sechirwere chetachiona kana sarcoidosis;
• aspergillary sinusitis iyo isingawanzoiti yeaspergillosis muzvivi;
• invasive aspergillosis kana utachiona ne Aspergillus fumigatus inotambanudza kubva pakufema kusvika kune dzimwe nhengo (uropi, mwoyo, chiropa, itsvo, nezvimwewo) kuburikidza neropa.

Kuongororwa kweaspergillosis

Inobva pakuongororwa kwekiriniki iyo inogona kuwedzeredzwa nekuongorora kwakadzama:

• kuongororwa kweiyo biological sample kubva munzvimbo ine hutachiona kuona fungal dhizaini;
• x-ray kana CT scan yenzvimbo ine utachiona.

Vanhu vanobatwa ne aspergillosis

Muzviitiko zvakawanda, muviri unokwanisa kurwisana neAspergillus uye kudzivirira aspergillosis. Chirwere ichi chinongoitika chete kana mucous membranes yakashandurwa kana kana immune system isisina simba.

Ngozi yekukura kweaspergillosis inonyanya kukwirira muzviitiko zvinotevera:

• asima;
• cystic fibrosis;
• nhoroondo yetibhii kana sarcoidosis;
• kuchinjwa kwenhengo, kusanganisira kuputika kwepfupa;
• kurapwa kenza;
• high dose uye kwenguva refu corticosteroid therapy;
• neutropenia kwenguva refu.

Zviratidzo zvekufema

Aspergillosis inokonzerwa nekusvibiswa kuburikidza nekufema. Inowanzokura mumapapu uye inoratidzwa nezviratidzo zvakasiyana-siyana zvekufema:

• chikosoro ;
• muridzo;
• kufema kunetseka.

Zvimwe zviratidzo

Zvichienderana nechimiro cheaspergillosis uye nzira yayo, zvimwe zviratidzo zvinogona kuoneka:

• kupindwa nechando ;
• sinusitis;
• rhinitis;
• musoro;
• zvikamu zve malaise;
• kuneta;
• kuonda;
• kurwadziwa muchipfuva;
• ropa sputum (hemoptysis).

Ichi chirwere cheAspergillus chinonyanya kurapwa nemishonga inorwisa fungal (eg voriconazole, amphotericin B, itraconazole, posaconazole, echinocandins, nezvimwewo).

Pane zvisizvo. Semuenzaniso, antifungal kurapwa haishande kune aspergilloma. Muchiitiko ichi, kurapwa kwekuvhiya kunogona kudiwa kuitira kubvisa fungal bhora. Nezve allergic bronchopulmonary aspergillosis, kurapwa kunobva pakushandiswa kwecorticosteroids neaerosols kana nemuromo.

Kudzivirira kunogona kusanganisira kutsigira dziviriro yezvirwere zvevanhu vasina kusimba uye kudzikisira kuratidzwa kwavo kune spores yefungi ye genus Aspergillus. Kune varwere vane njodzi yakakura, kuzviparadzanisa mukamuri isina hutachiona kunogona kuitwa kudzivirira kuitika kweaspergillosis inoparadza nemhedzisiro yakakomba.