Makore anodarika mashanu adarika, vesainzi vakaona kuti kudyiwa kwenyama yakakangwa – kusanganisira yakagochwa, nyama yakagochwa nenyama yakagochwa – kunowedzera njodzi yegomarara remuura zvakanyanya.
Izvi zvinodaro nekuti heterocyclic amines, iyo inoonekwa munyama yakabikwa, inokanganisa yakajairika metabolism. Zvisinei, maererano neongororo yezvokurapa yazvino, mamiriro ezvinhu nenyama yakakangwa akaipisisa kupfuura zvaimbofungwa.
Pamusoro pegomarara remudumbu, rinokonzeresawo chirwere cheshuga uye dementia, ndiko kuti, rinenge riine mhedzisiro yakafanana pamuviri seyakagadzirwa zvakanyanya, "kemikari" uye "yekukurumidza" chikafu, kana chikafu chakabikwa zvisizvo. Vanachiremba vane chokwadi chekuti mukana wekuita zvirwere zvakakomba, zvisingadzoreki unowedzera zvakaenzana nekuti munhu anodya kangani chikafu chakadaro - ingave burger yakazadzwa nemishonga inochengetedza kubva kuchidyiro kana "yakanaka yekare" yakadzika-yakakangwa steak.
Chidzidzo ichi chakaitwa neIcahn Chikoro cheMishonga muNew York uye chakaburitswa muAmerican science magazini Proceedings of the National Academy of Sciences. Mhedzisiro yacho inoratidza kuti chero nyama yakakangwa zvakanyanya (ingave pani-yakakangwa kana yakagochwa) yakabatana zvakananga nechimwe chirwere chakakomba - chirwere cheAlzheimer.
Mumushumo wavo, vanachiremba vakatsanangura zvakadzama maitiro ekuonekwa kweanonzi AGE panguva yekupisa kwekupisa kwenyama, "Advanced Glicated End products" (Advanced Glicated End products, kana AGE kwenguva pfupi - "age"). Zvinhu izvi zvichiri kudzidziswa zvishoma, asi masayendisiti atove nechokwadi chekuti zvinokuvadza zvakanyanya kumuviri uye zvinokonzeresa zvirwere zvisingaperi, kusanganisira chirwere cheAlzheimer uye senile dementia.
Masayendisiti akaedza pamakonzo erabhoritari, rimwe boka raidyiswa chikafu chakanyanya muzvigadzirwa zvekupedzisira zveglycation, uye rimwe boka raipihwa chikafu chine zvakaderedzwa zvemaAGE anokuvadza. Nekuda kwekugayiwa kwechikafu "chakaipa" muuropi hwe "nyama-inodya" mbeva, pakanga paine kuunganidzwa kunooneka kweakakuvadzwa beta-amyloid protein - chiratidzo chikuru chekuuya kwechirwere cheAlzheimer muvanhu. Panguva imwecheteyo, muviri wemakonzo aidya "utano" chikafu akakwanisa kumisa kugadzirwa kwechinhu ichi panguva yekufambisa kwechikafu.
Chimwe chikamu chekudzidza chakaitwa kune varwere vakwegura (vanopfuura makore makumi matanhatu) vanotambura nedementia. Ukama hwakananga hwakasimbiswa pakati pezvinyorwa zve AGEs mumuviri uye kupera simba kwemano enjere emunhu, pamwe chete nenjodzi yechirwere chemoyo. Dr. Helen Vlassara, uyo akatungamirira kuedza kwacho, akati: “Kuwana kwedu kunonongedzera kunzira iri nyore yokuderedza nayo ngozi yezvirwere izvi ndeyokudya zvokudya zvakaderera mumazera. Semuenzaniso, ichi chikafu chakabikwa pamusoro pekupisa kwakadzika nemvura yakawanda - nzira yekubika iyo yave ichizivikanwa kuvanhu kwemazana emakore akawanda.
Masayendisiti akatokurudzira kuisa chirwere cheAlzheimer se "Type XNUMX Diabetes" izvozvi. iyi fomu yedementia yakabatana zvakananga nekuwedzera kwemazinga ehuga muuropi. Dr. Vlassara akagumisa, kuti: “Kumwe kunzvera kunodiwa kuwana batano chaidzoidzo pakati pemaAGE nehosha dzakasiyana-siyana dze<em>metabolic nedzetsinga. (Parizvino, chinhu chimwe chete chinogona kutaurwa - Vegetarian) ...
Chikonzero chakanaka chekufunga kune avo vachiri kufunga nezve yakaitwa zvakanaka chop "chikafu chine hutano", uye panguva imwechete yakachengetedza kugona kufunga kwakadzikama!