LDH inosarudza kirasi yema enzymes, Lactase dehydrogenases. Anowanikwa kwese kwese mumuviri, mungave mumhasuru (uye kunyange pamwoyo), mumatishu emapapu kana mumasero eropa. Enzyme iprotein ine basa rekukonzeresa kuita mukati memuviri, nemamwe mazwi kukonzeresa kana kukurumidzira kuita kunowanzo kunonoka.

Kune marudzi akati wandei, kana kuti isoenzymes, anocherechedzwa nenhamba zvichienderana nenzvimbo yawo. Saka avo vemoyo kana uropi vanogamuchira chimiro cheLDH 1 uye 2, nepo avo emaplatelet uye lymph nodes ari LDH3, avo echiropa LDH 4 uye avo eganda LDH5.

Basa reLDH mukati memuviri nderekukonzeresa shanduko yepyruvate kuita lactate, uye zvinopesana. Aya maasidhi maviri ane basa rekufambisa simba pakati pemasero.

Cherechedza kuti inonziwo lactate dehydrogenase, kana lactic dehydrogenase, uye dzimwe nguva inofananidzirwa neLD.

Chido chekurapa cheLDH enzymes chiri pamusoro pezvose kuona kuwedzera kusingaite mukuvapo kwavo. Kazhinji, LDH inochengetwa mukati memasero emuviri. Asi kana matishu akakuvadzwa, anodurura, uye nekudaro anowedzera kuwedzera pyruvate mu lactate.

Kuvaziva munzvimbo chaidzo kana kutarisa maitiro avo mumuviri zvinogona kuita kuti zvikwanise kuona nzvimbo yakakuvadzwa nesero, kana kuongorora kuoma kwayo. Izvo zvinobatsirawo pakuona huwandu hwezvirwere, kubva kuanemia kusvika kugomarara (ona "Dudziro yemhedzisiro yeLDH").

Kuongororwa kwemuyero weLDH kunoitwa nesampling yeropa iri nyore. Kunyanya, marabhoritari anoongorora serum, iyo mvura inogezera zvinoumba ropa semasero matsvuku eropa. Kunyangwe iwo ekupedzisira ainewo LDH enzymes mumoyo yavo, iri pamusoro pese muyero weserum unokosha pakuona kuti nhanho yacho haina kujairika here kana kuti kwete.

Iko kukosha kweiyo assay yeLDH enzyme inoongororwa pa120 kusvika 246 U / L (mayunitsi parita).

Kutevera kuongororwa, chiremba anogona kuongorora mhedzisiro yakapihwa nerabhoritari, uye pamwe nekuona zvakasiyana siyana mumurwere. Kazhinji, zvichave zvakakosha kubatanidza chigumisiro ichi nehuwandu hwemamwe enzymes kana acids, nokuti kuwedzera nyore kana kuderera kweLDH kunogona kuva nemavambo akasiyana. Saka pane mikana yakasiyana yekupirikira.

Kana iyo LDH level yakakwira:

• Anemia

Kazhinji kazhinji inogona kuva yakaipa (inonziwo chirwere cheBiermer), kana hemolytic anemia. Mune yekupedzisira, autoantibodies inonamatira kumasero matsvuku eropa uye inoaparadza, izvo zvinowedzera huwandu hweLDH muropa.

• Cancers: Mamwe marudzi ekenza akadai neoplasias anobatanidzwawo nekukurumidza kukwira kweLDH.
• Infarction: Kutevera myocardial infarction, inobatanidza nekukuvadza kune matishu emwoyo, kuwedzera kwemazinga eLDH kunoonekwa mukati maawa gumi. Mari yacho inodonha zvakare mumavhiki maviri anotevera.
• AVC (chirevo chakafanana se infactus)
• Pancreatitis
• itsvo uye intestinal zvirwere
• Mononucleosis
• Pulmonary embolism
• angina pectoris
• Muscular dystrophy
• Hepatitis (chepfu kana chinovharira)
• Myopathy (zvichienderana nenzvimbo yechirwere)

Kana chiyero cheLDH chakaderera kana chakajairika:

Muchiitiko ichi ndechokuti hapana dambudziko riripo, kana kuti rinozivikanwa nenzira iyi, mumutumbi.

Usanetseka: Kunyange zvazvo urongwa hwezvirwere hunogona kutyisa avo vakave nemigumisiro yepamusoro yeLDH, zvakanaka kuyeuka kuti zvimwe zviitiko zvemazuva ose, zvakadai sekurovedza muviri, zvinogona kukonzera kukwira kwechinguva muLDH. muropa.

Kusiyana neizvi, hemolysis (kuputika kwemasero matsvuku eropa muropa) panguva yekuedzwa kunogona kukonzera nhema. Iyo LDH iripo mumasero matsvuku eropa ichapararira, uye nekudaro kukanganisa mhedzisiro.

Kutevera kuongororwa kwezinga reLDH, zvigumisiro zvichatumirwa kuna chiremba wako anogona kukurukura zvakare newe kana zvichidiwa. Kana zvigumisiro zvichiratidza kuvapo kwechirwere, saka iwe unongoendeswa kune nyanzvi iri mubvunzo.

Muchiitiko chegomarara, kutariswa nguva dzose kwezinga reLDH kunogona kuratidza kuve chiratidzo chekuti gomarara rakabudirira here kana kuti kwete, kuitira kuziva kana masero anotangwa akaparadzwa zvechokwadi kana kuti anorwisa dzimwe nhengo dzemuviri.