Utachiona Klebsiella pneumoniae is an enterobacterium inokonzera zvirwere zvakawanda uye zvakakomba, kunyanya nosocomial muFrance. Nhamba yemhando dze Klebsiella pneumoniae vakagadzira kurwisa kwakawanda kwemishonga inorwisa mabhakitiriya.

Klebsiella pneumoniae, yaimbozivikanwa seFriedlander's pneumobacillus, inonzi enterobacterium, ndiko kuti, bacillus ine gram-negative. Inowanikwa mumatumbo, mumhepo yepamusoro yevanhu uye mhuka dzine ropa rinodziya: inonzi inonzi commensal bacteria.

Inobata kusvika ku30% yevanhu vari mudumbu uye nasopharyngeal mucous membranes. Utachiona uhu hunowanikwawo mumvura, muvhu, mumiti nemuhuruva (kusvibiswa netsvina). Iri zvakare pathogen inokonzera zvirwere zvakasiyana-siyana:

• chirwere chemabayo,
• septicemies,
• zvirwere zve urinary tract infections,
• intestinal zvirwere,
• chirwere cheitsvo.

MuEurope, Klebsiella pneumoniae ndiyo inokonzera nharaunda yekufema zvirwere (mumataundi) muvanhu vasina simba (vanodhakwa, vane chirwere cheshuga, vakwegura kana avo vanotambura nezvirwere zvisingaperi zvekufema) uye kunyanya zvirwere zvenosocomial (zvakabatanidzwa muzvipatara) muvanhu vanorwara muchipatara (pneumonia, sepsis). uye kutapukira kwevacheche nevarwere vari mudzimba dzevanorwara zvakanyanya).

Utachiona Klebsiella pneumoniae inonyanya kuzivikanwa seyakakonzeresa nosocomial urinary uye intra-abdominal utachiona, sepsis, mabayo, uye hutachiona hwenzvimbo yekuvhiya. Inenge 8% yezvirwere zvenosocomial muEurope neUnited States zvinokonzerwa nebhakitiriya iri. Klebsiella pneumoniae zvirwere zvinowanzoitika mumadhipatimendi evacheche, kunyanya munzvimbo dzinochengetwa varwere zvakanyanya uye muvana vasati vasvika.

Zviratidzo zvechirwere cheKlebsiella pneumoniae

Zviratidzo zvehutachiona hweKlebsiella pneumoniae ndezviya zvehutachiona hwakanyanya hwebhakitiriya:

• high fever,
• kurwadziwa,
• kuderera kwe general condition,
• kutonhora.

Zviratidzo zvechirwere chekufema neKlebsiella pneumoniae

Zviratidzo zvechirwere chekufema neKlebsiella pneumoniae zvinowanzova pulmonary, ne sputum uye chikosoro, kuwedzera kune fivha.

Zviratidzo zvehutachiona hwehutachiona hunokonzerwa neKlebsiella pneumoniae

Zviratidzo zvehutachiwana hwehutachiwana hweKlebsiella pneumoniae zvinosanganisira kupisa uye kurwadziwa panguva yeweti, weti inonhuwa uye ine makore, kazhinji uye nekukasira kuda kuita weti, dzimwe nguva kuda kurutsa uye kurutsa.

Zviratidzo zvemeningitis zvinokonzerwa neKlebsiella pneumoniae

Zviratidzo zveKlebsiella pneumoniae meningitis (zvisingawanzoitiki) ndezvi:

• musoro,
• kupindwa nechando,
• kuchinja mamiriro ekuziva,
• matambudziko anokanganisa,
• septic shock.

Kuongororwa kwechokwadi kwechirwere cheKlebsiella pneumoniae kunobva pakuparadzaniswa uye kuzivikanwa kwebhakitiriya kubva kune samples dzeropa, weti, sputum, bronchial secretions kana nyama ine hutachiona. Kuzivikanwa kwebhakitiriya kunofanirwa kuperekedzwa nekuita kweantibiogram.

Antibiogram inzira yemurabhoritari inoita kuti zvikwanise kuyedza kunzwisiswa kwehutachiwana hwebhakitiriya maringe neimwe kana akawanda emishonga inorwisa mabhakitiriya, inoita seyakakosha pamhando dzeKlebsiella pneumoniae dzinowanzo rambana nemishonga yakawanda inorwisa mabhakitiriya.

Utachiona hweKlebsiella pneumoniae semamwe Enterobacteriaceae hwakatakurwa nemaoko, zvinoreva kuti utachiona uhu hunogona kutapurirwa nekubata ganda nezvinhu kana nzvimbo dzine utachiona. Muchipatara, utachiona uhwu hunotapurirwa kubva kune mumwe murwere kuenda kune mumwe kuburikidza nemaoko evanochengeta vanogona kutakura utachiona kubva kune mumwe murwere kuenda kune mumwe.

Hutachiona hwekunze kwechipatara Klebsiella pneumoniae hunogona kurapwa mutaundi necephalosporin (eg ceftriaxone) kana fluoroquinolone (eg levofloxacin).

Zvirwere zvakadzika neKlebsiella pneumoniae zvinorapwa nemishonga inobaya majekiseni. Vanowanzobatwa ne-broad-spectrum cephalosporins uye carbapenems (imipenem, meropenem, ertapenem), kana kunyange fluoroquinolones kana aminoglycosides. Sarudzo yekuti ndeupi mushonga unorapa unogona kuve wakaoma nekuda kwekuwana kwekupokana.

Mhando dzeKlebsiellia pneumoniae dzakagadzira kuramba kwakawanda kumishonga inorwisa mabhakitiriya. World Health Organization (WHO) inoronga utachiona uhwu pakati pe“utachiona hunokosha” 12 husingaurayiwi nemishonga. Semuyenzaniso, Klebsiella pneumoniae inogona kugadzira enzyme, carbapenemase, iyo inodzivisa kushanda kweanenge ese anonzi akafara spectrum β-lactam antibiotics.

Mune dzimwe nyika, mishonga inorwisa mabhakitiriya haichashandi pahafu yevarwere vanorapwa zvirwere zveK. pneumoniae. Kuwana kusawirirana nemishonga inorwisa mabhakitiriya kunogona kukanganisa mamwe makirasi emishonga akadai seaminoglycosides.