Conventional in vitro fertilization

Iyo in vitro fertilization chirongwa chekurapa chinoda kugadzwa kwakawanda nenyanzvi, dzinogadzirira vaviri vacho maitiro. Vaviri ava vanofanira kudzidziswa nezvematanho akaoma sejekiseni remishonga yehomoni, njodzi uye Zvikanganiso, naizvozvowo nguva yekumirira zvinodiwa. Mishonga yacho inodhura.

MuQuebec, kubvira 2010, iyo Régie de l'Assurance Maladie (RAMQ) yakamisa Chirongwa cheQuebec Assisted Procreation chinopa mahara masevhisi akazara ane chekuita nekushaya mbereko, kusanganisira mutengo wezvikamu zvitatu zvinokurudzirwa.⁹.

MuFrance, 4 in vitro fertilization miedzo inovharwa zvizere neHealth Inishuwarenzi.

1. Kukurudzira mazai

Danho rekutanga nderekupa mukadzi hormone therapy, kazhinji GnRH agonist (Gonadotropin Inoburitsa Hormone) kuitira kuzorora mazai (ona chikamu chemishonga), semuenzaniso Decapeptyl®, Suprefact®, Enantone® Synarel®, kana Lupron®.

Zvadaro, kurapwa kunobva kwavavarira kuwedzera nhamba yefollicles inogadzirwa ne ovaries uye kudzora nguva ye ovulation. Mukadzi anofanira kubaiwa majekiseni egonadotropin ane FSH kana LH kuita kuti follicles dzikure uye kuti dziburitse maoocyte akati wandei. Izvi semuenzaniso Puregon®, Gonal F®, Fostimon® Metrodin-HP®, Bravelle®, Humegon® Ménopur® Merional® Repronex® Fertinex® Fertinorm®,Humegon® Ménopur® Merional® Repronex® Fertinex® Fertinorm®,Elonva®, Luvéris®…

Kana mafollicles akura zvakakwana uye mazinga ehomoni akakwana, ovulation inokonzerwa nejekiseni rehomoni HCG (Human Chorionic Gonadotropin), semuenzaniso HCG endo 1500®, HCG endo 5000® (Fr), Pregnyl®, Choriomon®, Profasi-HP®, Chorex®, Novarel®, Ovitrelle® Ovidrel® ®

Pelvic ultrasound uye kuongororwa kweropa kunoitwa padanho rega rega kuongorora follicle kukura.

Hapasisina follicles, hapasisina mazai ...

Mazai emukadzi anowanzo bereka uye anosunungurwa zai rimwe chete rakura pa cycle. Kunyangwe izvi zvakakwana pakubata pamuviri kwakajairwa, kuti ibudirire in vitro fertilization, zvakanakira mazai akakura anofanira kuwanikwa. Saka zvakakosha kukurudzira basa remurwere re ovarian zvakanyanya kudarika nguva dzose. Mishonga inopihwa panguva yekurapa in vitro fertilization inokonzera kukura kwe multiple ovarian follicles, nokudaro kuwedzera huwandu hunobvira hwemazai, nokudaro mikana yekuwana implantable embryo.

2. Kuunganidzwa kwemaoocyte akura

Mushure memaawa makumi matatu nemaviri kusvika kumakumi matatu nematanhatu ekukurudzira mahomoni, maoocyte akaibva anounganidzwa pachishandiswa chubhu diki netsono inopinzwa mukati memukadzi. Kupindira uku kunoitwa pasi penzvimbo kana kuti general anesthesia ine ultrasound control nokuti inogona kurwadza zvikuru. Maoocyte anobva asarudzwa murabhoritari.

Le urume hunounganidzwa maawa mashoma zvisati zvaitika (kana kunyungudutswa zuva rimwe chetero), uye urume hunopatsanurwa kubva kumvura yemurume uye kuchengetwa pa37 ° C.

3. Fertilization

Maawa mashomanana mushure mekukohwa kwavo, spermatozoa uye oocytes zvinoiswa mukusangana mutsika yemvura kwemaawa akawanda pakupisa kwemuviri. Iyo motile spermatozoa inouya yega, pasina rubatsiro rwekunze, ichisangana neoocyte. Asi sperm rimwe chete ndiro richaita iyi. Kazhinji, paavhareji, 50% yeoocyte inogadzirwa.

Maoocyte (kana kuti zygotes) anotanga kuwanda. Mumaawa makumi maviri nemana, ma zygotes anova embryos kubva pamasero maviri kusvika mana.

4. Kuendeswa kwe embryo

Mazuva maviri kusvika kushanu pashure pokusangana, kamwana kacho kamwe kana kuti zviviri zvinoendeswa kuchibereko chomukadzi. Embryo transfer inzira iri nyore uye isingarwadzi inoitwa nekatheter yakatetepa uye inochinjika yakaiswa muchibereko. Embryo inoiswa mukati mechibereko uye inokura imomo kusvika yaiswa.

Mushure medanho iri, mukadzi anogona kazhinji kutangazve mabasa ake emazuva ese.

Imwe kana akawanda embryos (anonzi supernumeraries) anogona zvakare kuchengetwa nekuomeswa nechando kuti azoongororwa gare gare.

Mushure mezvo, chiremba anogona kupa kurapa kwehomoni, uye zvechokwadi magwaro ekuongororwa kwepamuviri kuti aone kana IVF yakashanda.

Mishonga yakawanda yekurapa dzimwe nguva inodiwa mimba isati yabudirira. Uye zvinosuruvarisa kuti vamwe vakaroorana havaiti pamuviri pasinei nekuedza kunoverengeka.

Zano pamberi peIVF: 

• Rega kusvuta (murume nemukadzi!), Nokuti zvinoderedza zvakanyanya mikana yekubata pamuviri.
• Rovedza muviri uye edza kuva nehuremu hune hutano. Zvinobatsira kuva nembereko yakanaka.
• Kune vakadzi: tora vhitamini B9 usati wabata pamuviri, sezvo izvi zvinoderedza njodzi yekusagadzikana mumwana asati azvarwa.
• Tora furuwenza (inogona kutungamirira kukubvisa pamuviri).