Izwi rokuti SIBO rinomirira "kukura kwebhakitiriya mudumbu" uye rinoreva kukura kwebhakitiriya kwemukati mudiki, iyo inoratidzirwa nehuwandu hwehuwandu hwebhakitiriya muchikamu ichi chemukati uye malabsorption. Chiratidzo chekiriniki chinowanzoitika manyoka, gasi uye zviratidzo zvemalabsorption. Izvo zvinokonzeresa kukura kwebhakitiriya ndeye anatomical (diverticulosis, blind loop, nezvimwewo) kana kushanda (kukanganisa mumatumbo motility, kusavapo kwegastric acid secretion). Kurapa kunosanganisira kudya kwakawanda-mafuta, kuderera kwe-carbohydrates, kutonga kwekushaiwa, kurapa kwe-broad-spectrum antibiotic therapy, uye kubviswa kwezvinhu zvinopa kudzivirira kudzokazve.

Izwi rokuti SIBO rinomirira "kukura kwebhakitiriya mudumbu" kana kukura kwebhakitiriya kwemukati mudiki. Iyo inoratidzirwa nenhamba yakawandisa yebhakitiriya mudumbu diki (> 105 / ml) iyo inogona kukonzera malabsorption kusagadzikana, kureva kusakwana kunyudzwa kwezvinhu zvekudya.

Pasi pemamiriro akajairwa, iyo proximal chikamu chemukati mudumbu chine isingasviki 105 mabhakitiriya / ml, kunyanya aerobic Gram-positive bacteria. Uku kushomeka kwebhakitiriya kunochengetwa ne:

• mhedzisiro yezvakajairwa intestinal contractions (kana peristalsis);
• zvakajairika gastric acid secretion;
• mucus;
• secretory immunoglobulins A;
• Ileocecal valve inoshanda.

Muchiitiko chekukura kwebhakitiriya, kuwanda kwebhakitiriya,> 105 / ml, inowanikwa mudumbu repamusoro. Izvi zvinogona kubatanidzwa ne:

• kusagadzikana kana kuchinja kweanatomical mudumbu uye / kana dumbu diki (diverticulosis yedumbu diki, kuvhiyiwa mapofu zvishwe, post-gastrectomy mamiriro, kuomesesa kana chidimbu zvipingamupinyi) zvinokurudzira kunonoka kwemukati mukati, zvichikonzera kukura kwebhakitiriya; 
• kuvhiringidzika kwemotokari kwechirwere chekudya chakabatana nechirwere cheshuga neuropathy, scleroderma, amyloidosis, hypothyroidism kana idiopathic intestinal pseudo-obstruction iyo inogonawo kuderedza kubudiswa kwebhakitiriya;
• kusavapo kwegastric acid secretion (achlorhydria), inogona kunge iri yemishonga kana yekuvhiya.

Mabhakitiriya anonyanya kuzivikanwa ekukura kwebhakitiriya mudumbu mudiki anosanganisira:

• Streptococcus sp;
• Bacteroides sp;
• Escherichia coli;
• Staphylococcus sp;
• Klebsiella sp;
• uye Lactobacillus.

Aya mabhakitiriya akawandisa anoderedza kunwisa kwemasero emudumbu uye anodya zvinovaka muviri, zvinosanganisira makabhohaidhiretsi uye vhitamini B12, izvo zvinogona kuguma necarbohydrate malabsorption uye kushomeka kwekudya uye vhitamini. Uyezve, mabhakitiriya aya anoitawo pane bile munyu nekuvashandura, anodzivirira kuumbwa kwe micelles inotungamira kune malabsorption ye lipids. Kukura kwebhakitiriya kwakanyanya pakupedzisira kunotungamirira kumaronda emudumbu mucosa. 

Varwere vazhinji havana zviratidzo. Pamusoro pekurasikirwa kwehuremu hwekutanga kana kushomeka mune zvinovaka muviri uye mavhitamini anonyungudika nemafuta (kunyanya mavhitamini A uye D), zviratidzo zvinowanzoitika zvinosanganisira:

• kusagadzikana mudumbu;
• manyoka akawanda kana mashoma;
• steatorrhea, kureva, huwandu husina kujairika hwema lipids muchituru, zvichibva pa malabsorption ye lipids uye kukuvadza kune mucous membranes;
• bloating;
• gasi rakawandisa, rinokonzerwa nemagasi anogadzirwa nekuvirisa kwemakhahydrates.

Mishonga inorwisa mabhakitiriya inofanira kuiswa panzvimbo, kwete kupedza maruva ebhakitiriya asi kuigadzirisa kuitira kuwana kuvandudzwa kwezviratidzo. Nekuda kwechimiro chepolymicrobial chemaruva emudumbu, yakakura spectrum antibiotics inodiwa kuvhara ese aerobic uye anaerobic mabhakitiriya.

Kurapa kweSIBO kunobva pakutora, kwemazuva gumi kusvika gumi nemana, nemuromo, imwe kana maviri emishonga inorwisa mabhakitiriya:

• Amoxicillin / clavulanic acid 500 mg katatu pazuva;
• Cephalexin 250 mg 4 nguva / zuva;
• Trimethoprim / sulfamethoxazole 160 mg / 800 mg kaviri / zuva;
• Metronidazole 250 kusvika 500 MG 3 kana 4 nguva / zuva;
• Rifaximin 550 mg katatu pazuva.

Uku kurapwa kwemishonga inorwisa mabhakitiriya kwakafaranuka kunogona kuita cyclical kana kugadziridzwa, kana zviratidzo zvikazoonekwa zvakare.

Panguva imwecheteyo, zvinhu zvinokurudzira kuwedzera kwebhakitiriya (anatomical uye kusashanda zvakanaka) kunofanirwa kubviswa uye kushandurwa kwekudya kunokurudzirwa. Zvechokwadi, mabhakitiriya akawandisa anonyanya kuisa makhahydrates mumatumbo lumen pane lipids, kudya kwakawanda mumafuta uye kuderera mufiber uye carbohydrate - lactose isina - inokurudzirwa. Kushaikwa kwevhitamini, kunyanya vhitamini B12, inofanirawo kugadziriswa.