Tako Tsubo syndrome chirwere chetsandanyama yemoyo inoonekwa nekushomeka kwekupedzisira kweiyo ventricle yekuruboshwe. Kubva payakatsanangurwa kwekutanga muJapan muna 1990, chirwere cheTako Tsubo chakazivikanwa pasi rose. Nekudaro, mushure memakumi matatu emakore ekuyedza kukuru kuti unzwisise chirwere ichi, ruzivo rwezvino rwunoramba rwakaganhurwa.

Tako Tsubo syndrome chirwere chetsandanyama yemwoyo inoonekwa nekushomeka kwekupedzisira kweiyo ventricle yekuruboshwe.

Iyi cardiomyopathy inotora zita rayo kubva kuJapan "octopus trap", nekuda kwechimiro icho ventricle yekuruboshwe inotora muzviitiko zvakawanda: kubhururuka kumusoro kwemoyo uye kudzikira pazasi payo. Takotsubo syndrome inozivikanwa se "broken heart syndrome" uye "apical ballooning syndrome".

Takotsubo syndrome inosvika 1 kusvika 3% yevarwere vese pasirese. Zvinoenderana nezvinyorwa, vangangoita 90% yevarwere vane chirwere ichi vakadzi vari pakati pemakore makumi matanhatu nematanhatu nemakore makumi manomwe. Vakadzi vanodarika makumi mashanu nemashanu vane mukana wakapetwa kashanu wekubata chirwere ichi kupfuura vakadzi vari pasi pemakumi mashanu nemashanu uye kakapetwa kagumi njodzi kupinda varume.

Zviratidzo zvakajairika zveTako Tsubo syndrome ndezvi:

• Kurwadziwa kwepfupa kwakapinza;
• Dyspnea: kuoma kana kunetseka kufema;
• A syncope: kurasikirwa kamwe kamwe kwekuziva.

Chiratidziro chekiriniki cheTakotsubo syndrome inokonzerwa nekushushikana kwakanyanya kwemuviri kunogona kudzorwa nekuratidzwa kwechirwere chakakomba. Mune varwere vane sitirokiki sitiroko kana kubatwa, Takotsubo chirwere hachiwanzo kuperekedzwa nemarwadzo echifuva. Kusiyana neizvi, varwere vane kushushikana kwepfungwa vane huwandu hwakanyanya hwekurwadziwa kwepfupa uye palpitations.

Izvo zvakakosha kuti uzive kuti subset yevarwere vane Takotsubo syndrome inogona kuuya nezviratidzo zvinomuka kubva kumatambudziko ayo:

• Kutadza kwemoyo;
• Edema yemapapu;
• Tsaona yematsipa tsaona;
• Cardiogenic kuvhunduka: kutadza kwepombi pombi;
• Cardiac kusungwa;

Kuongororwa kweTakotsubo syndrome kazhinji kwakaoma kusiyanisa kubva kune acute myocardial infarction. Zvisinei, mune vamwe varwere zvinogona kuonekwa sezvinei kuburikidza nekuchinja kwe electrocardiogram (ECG) kana kusimuka kamwe kamwe kwemoyo biomarkers - zvigadzirwa zvinobudiswa muropa kana mwoyo wakuvadzwa.

Coronary angiography ine kuruboshwe ventriculography - yepamusoro uye yakawandisa radiography yeboshwe ventricular basa - inoonekwa segoridhe yakajairwa yekuongorora chishandiso kutonga kunze kana kusimbisa chirwere.

Chishandiso, chinonzi chikamu cheInterTAK, chinogona zvakare kukurumidza kutungamira kuongororwa kweTakotsubo syndrome. Rated kubva pamapoinzi zana, iyo InterTAK mamaki yakavakirwa pamatanho manomwe: 

• Iyo mukadzi pabonde (makumi maviri neshanu poindi);
• Kuvapo kwekushushikana kwepfungwa (makumi maviri nemana mapfumbamwe);
• Kuvapo kwekushushikana kwemuviri (gumi nematanhatu);
• Kushaikwa kwekusuwa kwechikamu che ST pane iyo electrocardiogram (gumi nemaviri);
• Nhoroondo yepfungwa (gumi nemana);
• Nhoroondo yeNeological (9 mapoinzi);
• Kuwedzerwa kwenguva yenguva yeQT pane iyo electrocardiogram (nhanhatu).

Chikamu chinopfuura makumi manomwe chinosanganisirwa nehumwe mukana wechirwere chakaenzana ne70%.

Mazhinji Takotsubo syndromes anokonzereswa nezviitiko zvinonetsa. Zvinokonzera muviri zvakajairika kupfuura kushungurudzika mupfungwa. Kune rimwe divi, varwere vechirume vanowanzo kanganiswa nechiitiko chinoshushikana mumuviri, nepo kuvakadzi chinokonzeresa chepfungwa chinowanzoonekwa. Chekupedzisira, kesi dzinoitikawo mukushaikwa kuri pachena kushushikana.

Zvinokonzera muviri

Pakati pezvinokonzera muviri ndezvi:

• Zvepanyama zviitiko: kurima gadheni kana mutambo;
• Mamiriro akasiyana ekurapa kana nenjodzi mamiriro: asthma, yekupedzisira-nhanho chisingaperi pulmoni chirwere), pancreatitis, cholecystitis (kuzvimba kwegongo), pneumothorax, kukuvara kunorwadza, sepsis, chemotherapy, radiotherapy, nhumbu, chikamu chesaarean, mheni, padyo-kunyura, hypothermia, cocaine, doro kana opioid kubvisa, carbon monoxide chepfu, nezvimwe.
• Mimwe mishonga, inosanganisira dobutamine kushushikana bvunzo, electrophysiological bvunzo (isoproterenol kana epinephrine), uye beta-agonists yeasthma kana chisingaperi obstructive pulmonary chirwere;
• Kuvharika kwakasimba kweacoronary arteri;
• Kuda kwehurongwa hwemitsipa: sitiroko, kushungurudzika kwemusoro, kubuda ropa mukati kana kusagadzikana;

Zvinokonzera zvepfungwa

Pakati pezvikonzero zvepfungwa ndezvi:

• Kushungurudzika: kufa kwenhengo yemhuri, shamwari kana chipfuwo;
• Kukakavadzana pakati pevamwe: kurambana kana kuparadzana kwemhuri;
• Kutya nekuvhunduka: kuba, kurova kana kutaura pamberi pevanhu;
• Hasha: kupopotedzana nenhengo yemhuri kana muridzi wemba;
• Kufunganya: kurwara pachezvako, kuchengetwa kwevana kana kushaya pekugara;
• Matambudziko emari kana ehunyanzvi: kubhejera kurasikirwa, bhizimusi kubhuroka kana kurasikirwa nebasa;
• Zvimwewo: kumhan'arwa, kusavimbika, kuvharirwa nhengo yemhuri, kurasikirwa mukuita kwepamutemo, nezvimwe.
• Njodzi dzinongoitika dzega dzakadai sekudengenyeka kwenyika nemafashama emvura.

Chekupedzisira, zvinofanirwa kucherechedzwa kuti zvinokonzeresa zvechirwere hazvigare zvisina kunaka: zvakanaka zviitiko zvemoyo zvinogona kukonzeresa chirwere ichi: pati inoshamisa yemabiko, chokwadi chekuhwina jackpot uye nhaurirano yakanaka yebasa, nezvimwe. inorondedzerwa se "mufaro moyo chirwere".

Mushure mechiitiko chekutanga cheTakotsubo syndrome, varwere vari panjodzi yekudzokazve, kunyangwe makore akatevera. Zvimwe zvinhu zvinoita sekuratidza kuvandudzwa kwekupona pagore rimwe uye kuderera kweichi chiitiko chekudzokazve:

• ACE inhibitors: dzinodzivisa kushandurwa kwe angiotensin I kuva angiotensin II - enzyme inokonzeresa kuti tsinga dzeropa - uye dziwedzere huwandu hwebradykinin, enzyme ine vasodilating mhedzisiro;
• Angiotensin II vanopesana nevanopikisa (ARA II): vanovhara chiito cheiyo enzyme isingazivikanwe.
• An antiplatelet drug (APA) inogona kutariswa pane kesi-ne-kesi hwaro mushure mekuchengetwa muchipatara mune chiitiko chakakomba chekuruboshwe kwemhepo ventricular kusagadzikana kwakabatana nekuramba kuri kuitika kweapical bloating.

Basa rinogona kuita remakatecholamines akawandisa - makemikari makemikari akagadzirwa kubva ku tyrosine uye kuita sehormone kana neurotransmitter, ayo akajairika ari adrenaline, norepinephrine uye dopamine - mukukudziridzwa kweTakotsubo cardiomyopathy yakurukurwa kwenguva refu, uye saizvozvo, beta blockers yakurudzirwa senzira yekurapa. Nekudaro, zvinoita sekunge hazvishande mukufamba kwenguva: chiyero chekudzokorora che30% chinoonekwa kune varwere vanorapwa ne beta-blockers.

Dzimwe nzira dzokurapa dzinoramba dzichiongororwa, senge maanticoagulants, kurapwa kwehormone kwekuguma kuenda kumwedzi kana kurapwa kwepfungwa.

Izvo zvine njodzi njodzi yeTakotsubo syndrome inogona kuiswa muzvikamu zvitatu zvikuru.

• Hormonal zvinhu: kupesana kunoshamisa kwevakadzi vanonzi postmenopausal kunopa hunyanzvi hwehomoni. Yepasi yeserogenji mushure mekuguma kuenda kumwedzi kunogona kuwedzera kugona kwevakadzi kuTakotsubo syndrome, asi data rakarongeka rinoratidza kubatana kuri pachena pakati pezviviri kuri kushomeka kusvika zvino;
• Mageneti zvinhu: zvinokwanisika kuti hutachiona hunogona kusangana pamwe nezvakatipoteredza kuti tifarire kutanga kwechirwere, asi pano zvakare, zvidzidzo zvinotendera kuti chirevo ichi chiitwe hachina;
• Psychiatric uye Neurological Disorders: Kuwanda kwakanyanya kwepfungwa - kushushikana, kushushikana, kutadziswa - uye kusagadzikana kwetsinga kwakataurwa kune varwere vane Takotsubo syndrome.